Success Metrics

Clinical Success Rate
78.5%

Based on 95 completed trials

Completion Rate
79%(95/121)
Active Trials
42(21%)
Results Posted
55%(52 trials)
Terminated
26(13%)

Phase Distribution

Ph early_phase_1
3
2%
Ph not_applicable
8
4%
Ph phase_4
1
1%
Ph phase_1
51
26%
Ph phase_3
19
10%
Ph phase_2
116
58%

Phase Distribution

54

Early Stage

116

Mid Stage

20

Late Stage

Phase Distribution198 total trials
Early Phase 1First-in-human
3(1.5%)
Phase 1Safety & dosage
51(25.8%)
Phase 2Efficacy & side effects
116(58.6%)
Phase 3Large-scale testing
19(9.6%)
Phase 4Post-market surveillance
1(0.5%)
N/ANon-phased studies
8(4.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.6%

95 of 129 finished

Non-Completion Rate

26.4%

34 ended early

Currently Active

42

trials recruiting

Total Trials

200

all time

Status Distribution
Active(50)
Completed(95)
Terminated(34)
Other(21)

Detailed Status

Completed95
Recruiting28
Terminated26
unknown20
Active, not recruiting14
Not yet recruiting8

Development Timeline

Analytics

Development Status

Total Trials
200
Active
42
Success Rate
78.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (1.5%)
Phase 151 (25.8%)
Phase 2116 (58.6%)
Phase 319 (9.6%)
Phase 41 (0.5%)
N/A8 (4.0%)

Trials by Status

not_yet_recruiting84%
completed9548%
unknown2010%
suspended11%
terminated2613%
active_not_recruiting147%
recruiting2814%
withdrawn84%

Recent Activity

Clinical Trials (200)

Showing 20 of 200 trialsScroll for more
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT03779854Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT01511562Phase 2

Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma

Completed
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT07819812

Thiotepa-Based Conditioning for Haploidentical Hematopoietic Stem Cell Transplantation in Older Patients With Severe Aplastic Anemia

Not Yet Recruiting
NCT03980769Phase 2

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disorders

Recruiting
NCT03597594Phase 1

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Active Not Recruiting
NCT03849651Phase 2

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Active Not Recruiting
NCT06680661Phase 2

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Suspended
NCT01949129Phase 2

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
NCT06687772Phase 2

CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant

Recruiting
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT03126916Phase 3

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Recruiting
NCT06158828Phase 1

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Recruiting
NCT07778940Phase 2

Thiotepa Administration Via Ommaya Reservoir for Leptomeningeal Metastases in Non-Small Cell Lung Cancer Resistant to EGFR-TKI.

Not Yet Recruiting
NCT07565220Phase 1

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

Recruiting
NCT03630211Phase 2

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

Recruiting
NCT03653338Phase 1

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Recruiting
NCT07759102Phase 1

Allogeneic ORCA-Q Stem Cell Transplant for the Treatment of Relapsed and Refractory High Risk Multiple Myeloma

Not Yet Recruiting
NCT04708054Phase 2

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
200