Success Metrics

Clinical Success Rate
78.3%

Based on 94 completed trials

Completion Rate
78%(94/120)
Active Trials
42(21%)
Results Posted
54%(51 trials)
Terminated
26(13%)

Phase Distribution

Ph phase_1
50
25%
Ph not_applicable
8
4%
Ph phase_3
19
10%
Ph early_phase_1
3
2%
Ph phase_4
1
1%
Ph phase_2
115
58%

Phase Distribution

53

Early Stage

115

Mid Stage

20

Late Stage

Phase Distribution196 total trials
Early Phase 1First-in-human
3(1.5%)
Phase 1Safety & dosage
50(25.5%)
Phase 2Efficacy & side effects
115(58.7%)
Phase 3Large-scale testing
19(9.7%)
Phase 4Post-market surveillance
1(0.5%)
N/ANon-phased studies
8(4.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.4%

94 of 128 finished

Non-Completion Rate

26.6%

34 ended early

Currently Active

42

trials recruiting

Total Trials

197

all time

Status Distribution
Active(49)
Completed(94)
Terminated(34)
Other(20)

Detailed Status

Completed94
Recruiting28
Terminated26
unknown20
Active, not recruiting14
Withdrawn8

Development Timeline

Analytics

Development Status

Total Trials
197
Active
42
Success Rate
78.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (1.5%)
Phase 150 (25.5%)
Phase 2115 (58.7%)
Phase 319 (9.7%)
Phase 41 (0.5%)
N/A8 (4.1%)

Trials by Status

unknown2010%
withdrawn84%
active_not_recruiting147%
terminated2613%
not_yet_recruiting74%
completed9448%
recruiting2814%

Recent Activity

Clinical Trials (197)

Showing 20 of 197 trialsScroll for more
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06942039Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Recruiting
NCT03849651Phase 2

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Active Not Recruiting
NCT07052370Phase 1

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Completed
NCT07616154Phase 2

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

Not Yet Recruiting
NCT02220985Phase 2

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Completed
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT03779854Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Recruiting
NCT07566377Phase 2

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Active Not Recruiting
NCT04872595Phase 2

A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

Active Not Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT04217278Phase 2

A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT

Active Not Recruiting
NCT06158828Phase 1

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Recruiting
NCT07563920Not Applicable

TBF Conditioning Regimen for Haploidentical Stem Cell Transplantation in Elderly AML Patients in First Complete Remission

Not Yet Recruiting
NCT07565220Phase 1

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

Not Yet Recruiting
NCT03263559Phase 2

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Completed
NCT06195891Phase 1

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Recruiting
NCT06807606Phase 2

Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
197