NCT00013858

Brief Summary

This study is designed to examine the effects of prenatal exposure to environmental contaminants on cognitive and behavioral development and physical growth in two groups of Inuit infants-one in Northern Quebec; the other in Greenland.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
280

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 1997

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1997

Completed
4.2 years until next milestone

First Submitted

Initial submission to the registry

March 30, 2001

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 3, 2001

Completed
10.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

April 14, 2015

Status Verified

April 1, 2015

Enrollment Period

14.6 years

First QC Date

March 30, 2001

Last Update Submit

April 13, 2015

Conditions

Mercury PoisoningLead Poisoning

Keywords

methylmercuryPCBsleadfish consumptionbreast-feeding

Eligibility Criteria

Age1 Day - 1 Day
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
infant born during recruitment period to a mother who is a resident of Povungnituk, Inukjuak, and Kuujjuarapik, Quebec or Nuuk, Greenland

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Public Health Centre of Quebec

Beauport, Quebec, Canada

Location

Related Publications (4)

  • Dewailly, E., Bruneau, S., Ayotte, P., Liliberte, C., Gingras, S. Belander, D. and Ferron, L. Health status at birth of Inuit newborn prenatally exposed to organochlorines - Chemosphre, 1993, 27: 359-366.

    BACKGROUND

  • Dewailly E, Ayotte P, Bruneau S, Laliberte C, Muir DC, Norstrom RJ. Inuit exposure to organochlorines through the aquatic food chain in arctic quebec. Environ Health Perspect. 1993 Dec;101(7):618-20. doi: 10.1289/ehp.93101618.

    PMID: 8143594BACKGROUND

  • Jacobson SW, Fein GG, Jacobson JL, Schwartz PM, Dowler JK. The effect of intrauterine PCB exposure on visual recognition memory. Child Dev. 1985 Aug;56(4):853-60.

    PMID: 3930167BACKGROUND

  • Jacobson JL, Jacobson SW. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N Engl J Med. 1996 Sep 12;335(11):783-9. doi: 10.1056/NEJM199609123351104.

    PMID: 8703183BACKGROUND

MeSH Terms

Conditions

Mercury PoisoningLead PoisoningBreast Feeding

Condition Hierarchy (Ancestors)

Heavy Metal PoisoningPoisoningChemically-Induced DisordersFeeding BehaviorBehavior

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

March 30, 2001

First Posted

April 3, 2001

Study Start

January 1, 1997

Primary Completion

August 1, 2011

Study Completion

August 1, 2011

Last Updated

April 14, 2015

Record last verified: 2015-04

Locations

CA(1)