Study of Arthritis and Related Conditions
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions
Sponsor study identifier
Secondary identifiers
observational
697
1 country
1
Study Start
October 3, 2000
Actual (reported)Primary Completion
March 10, 2021
Actual (reported)Study Completion
March 10, 2021
Actual (reported)This research protocol will recruit patients with arthritis and related conditions for the purpose of screening patients for treatment protocols, and evaluating the natural history of arthritis and related conditions. Patients will be evaluated clinically, radiographically and serologically, and standardized data will be uniformly collected on all patients. Additional imaging using sensitive MRI methods will be obtained in some patients. The collected blood and tissue will be utilized for laboratory studies to continue research on the pathogenic mechanisms of rheumatoid arthritis and related autoimmune joint diseases. Data from the history and physical examination as well as several disability questionnaires in the adult and pediatric population will be used to phenotypically characterize these patients and assess outcome and functional status. Any medical care recommended or provided to the patients will be consistent with routine standards of practice and provided in consultation with the patient's referring physician.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 10, 2021
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 3, 2000
Actual (reported)October 4, 2000
Actual (reported)October 5, 2000
Actual (reported)March 10, 2021
Actual (reported)March 10, 2021
Actual (reported)Determine patterns of arthritis
Evaluate natural history and disease trajectories in rheumatoid arthritis
End of the study
Confirmatory Studies In RA and related diseases
End of the study
Co-culture experiments using synovial tissue and surgical cartilage specimens
End of the study
MRI Imaging in RA and related diseases
End of the study
Collection of DNA in RA and related diseases
End of the study
Evaluation of early disability in RA and related diseases
End of the study
Subjects with known or suspected arthritis will be evaluated longitudinally
Subjects with known or suspected arthritis
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, 20892, United States
James D Katz, M.D.
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
697 participants (actual enrollment reported by the registry).
First Submitted
October 4, 2000
First Posted
October 5, 2000
Study Start
October 3, 2000
Actual (reported)dnaJ Peptide for Relieving Rheumatoid Arthritis
Contact the study team to confirm eligibility.
Primary Completion
March 10, 2021
Actual (reported)Study Completion
March 10, 2021
Actual (reported)Last Updated
March 12, 2021
Record last verified: 2021-03
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Source: ClinicalTrials.gov.
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