NCT00005263

Brief Summary

To determine whether postprandial lipoproteins were associated with atherosclerosis, and if so, whether the association was statistically independent of that between fasting lipoproteins and atherosclerosis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
205

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 1990

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 1990

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 1995

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 1995

Completed
4.6 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
Last Updated

December 24, 2015

Status Verified

December 1, 2015

Enrollment Period

5.3 years

First QC Date

May 25, 2000

Last Update Submit

December 22, 2015

Conditions

AtherosclerosisCardiovascular DiseasesHeart DiseasesCarotid Artery DiseasesMyocardial Ischemia

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Populations undergoing diagnostic exercise electrocardiographic or thallium stress tests at our medical centers.

You may qualify if:

  • Men and Women 18 years and older
  • Undergoing diagnostic exercise electrocardiographic or thallium stress tests at our medical centers

You may not qualify if:

  • Prior diagnosis of coronary artery disease (CAD)
  • Unable to fast due to health reasons

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Columbia University

New York, New York, 10032, United States

Location

Related Publications (2)

  • Ginsberg HN, Jones J, Blaner WS, Thomas A, Karmally W, Fields L, Blood D, Begg MD. Association of postprandial triglyceride and retinyl palmitate responses with newly diagnosed exercise-induced myocardial ischemia in middle-aged men and women. Arterioscler Thromb Vasc Biol. 1995 Nov;15(11):1829-38. doi: 10.1161/01.atv.15.11.1829.

    PMID: 7583562BACKGROUND

  • Sharrett AR, Chambless LE, Heiss G, Paton CC, Patsch W. Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb Vasc Biol. 1995 Dec;15(12):2122-9. doi: 10.1161/01.atv.15.12.2122.

    PMID: 7489232BACKGROUND

MeSH Terms

Conditions

AtherosclerosisCardiovascular DiseasesHeart DiseasesCarotid Artery DiseasesMyocardial Ischemia

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Henry Ginsberg, MD

    Herbert and Florence Irving Professor of Medicine; Director, Columbia University Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

July 1, 1990

Primary Completion

November 1, 1995

Study Completion

November 1, 1995

Last Updated

December 24, 2015

Record last verified: 2015-12

Locations

US(1)