NCT00005223

Brief Summary

To examine the complex interactions among the traditional cardiovascular risk factors, particularly lipoprotein and apoprotein levels, genetic and other characteristics, and lifestyle habits in elderly women.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 1988

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1988

Completed
4.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 1993

Completed
7.2 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
Last Updated

May 13, 2016

Status Verified

April 1, 2001

First QC Date

May 25, 2000

Last Update Submit

May 12, 2016

Conditions

Cardiovascular DiseasesHeart DiseasesCoronary Disease

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (13)

  • Vogt MT, Cauley JA, Kuller LH, Nevitt MC. Bone mineral density and blood flow to the lower extremities: the study of osteoporotic fractures. J Bone Miner Res. 1997 Feb;12(2):283-9. doi: 10.1359/jbmr.1997.12.2.283.

    PMID: 9041062BACKGROUND

  • Vogt MT, Cauley JA, Kuller LH. Apolipoprotein E phenotype, arterial disease, and mortality among older women: the study of osteoporotic fractures. Genet Epidemiol. 1997;14(2):147-56. doi: 10.1002/(SICI)1098-2272(1997)14:23.0.CO;2-4.

    PMID: 9129960BACKGROUND

  • Vogt MT, Nevitt MC, Cauley JA. Back problems and atherosclerosis. The Study of Osteoporotic Fractures. Spine (Phila Pa 1976). 1997 Dec 1;22(23):2741-7. doi: 10.1097/00007632-199712010-00008.

    PMID: 9431608BACKGROUND

  • Cauley JA, Gutai JP, Kuller LH, Powell JG. The relation of endogenous sex steroid hormone concentrations to serum lipid and lipoprotein levels in postmenopausal women. Am J Epidemiol. 1990 Nov;132(5):884-94. doi: 10.1093/oxfordjournals.aje.a115731.

    PMID: 2239903BACKGROUND

  • Vogt MT, Cauley JA, Kuller LH, Nevitt MC. Functional status and mobility among elderly women with lower extremity arterial disease: the Study of Osteoporotic Fractures. J Am Geriatr Soc. 1994 Sep;42(9):923-9. doi: 10.1111/j.1532-5415.1994.tb06581.x.

    PMID: 8064098BACKGROUND

  • Danielson ME, Cauley JA, Rohay JM. Physical activity and its association with plasma lipids and lipoproteins in elderly women. Ann Epidemiol. 1993 Jul;3(4):351-7. doi: 10.1016/1047-2797(93)90061-8.

    PMID: 8275210BACKGROUND

  • Cauley JA, Gutai JP, Glynn NW, Paternostro-Bayles M, Cottington E, Kuller LH. Serum estrone concentrations and coronary artery disease in postmenopausal women. Arterioscler Thromb. 1994 Jan;14(1):14-8. doi: 10.1161/01.atv.14.1.14.

    PMID: 8274469BACKGROUND

  • Carson CA, Cauley JA, Caggiula AW. Relation of caffeine intake to blood lipids in elderly women. Am J Epidemiol. 1993 Jul 15;138(2):94-100. doi: 10.1093/oxfordjournals.aje.a116839.

    PMID: 8342534BACKGROUND

  • Vogt MT, Cauley JA, Newman AB, Kuller LH, Hulley SB. Decreased ankle/arm blood pressure index and mortality in elderly women. JAMA. 1993 Jul 28;270(4):465-9.

    PMID: 8320785BACKGROUND

  • Cauley JA, Eichner JE, Kamboh MI, Ferrell RE, Kuller LH. Apo E allele frequencies in younger (age 42-50) vs older (age 65-90) women. Genet Epidemiol. 1993;10(1):27-34. doi: 10.1002/gepi.1370100104.

    PMID: 8472931BACKGROUND

  • Vogt MT, Cauley JA, Kuller LH, Hulley SB. Prevalence and correlates of lower extremity arterial disease in elderly women. Am J Epidemiol. 1993 Mar 1;137(5):559-68. doi: 10.1093/oxfordjournals.aje.a116709.

    PMID: 8465807BACKGROUND

  • Ganguli M, Cauley JA, DeKosky ST, Kamboh MI. Dementia among elderly apolipoprotein E type 4/4 homozygotes: a prospective study. Genet Epidemiol. 1995;12(3):309-11. doi: 10.1002/gepi.1370120308.

    PMID: 7557352BACKGROUND

  • Cauley JA, Zmuda JM, Yaffe K, Kuller LH, Ferrell RE, Wisniewski SR, Cummings SR. Apolipoprotein E polymorphism: A new genetic marker of hip fracture risk--The Study of Osteoporotic Fractures. J Bone Miner Res. 1999 Jul;14(7):1175-81. doi: 10.1359/jbmr.1999.14.7.1175.

    PMID: 10404018BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesCoronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular Diseases

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

April 1, 1988

Study Completion

March 1, 1993

Last Updated

May 13, 2016

Record last verified: 2001-04