Stanford Five-City Multifactor Risk Reduction Study
2 other identifiers
observational
2,504
0 countries
N/A
Brief Summary
To conduct a large-scale demonstration and education project designed to evaluate the feasibility and effectiveness of long-term community health education directed toward lowering cardiovascular disease risk, morbidity, and mortality. Targeted risk factors included general lifestyle, smoking, blood pressure, nutrition and weight, and exercise. The program was evaluated by biennial cross-sectional independent surveys, longitudinal studies, and morbidity and mortality surveillance.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 1978
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 1978
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 1994
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 1994
CompletedFirst Submitted
Initial submission to the registry
May 25, 2000
CompletedFirst Posted
Study publicly available on registry
May 26, 2000
CompletedFebruary 16, 2021
February 1, 2021
16 years
May 25, 2000
February 12, 2021
Conditions
Eligibility Criteria
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Sponsors & Collaborators
Related Publications (72)
Farquhar JW, Fortmann SP, Maccoby N, Wood PD, Haskell WL, et al: The Stanford Five City Project: An Overview. In: Matarazzo JD, Miller NE, Weiss SM, Herd JA & Weiss SM (Eds), Behavioral Health: A Handbook of Health Enhancement and Disease Prevention. John Wiley & Sons, Inc., Silver Spring, MD, 1154-1165, 1984
BACKGROUNDFortmann SP, Rogers T, Vranizan K, Haskell WL, Solomon DS, Farquhar JW. Indirect measures of cigarette use: expired-air carbon monoxide versus plasma thiocyanate. Prev Med. 1984 Jan;13(1):127-35. doi: 10.1016/0091-7435(84)90045-8.
PMID: 6609353BACKGROUNDSolomon DS, Maccoby N: Communication as a Model for Health Enhancement. In: Matarazzo JD, Miller NE, Weiss SM, Herd JA and Weiss SM (Eds), Behavioral Health: A Handbook of Health Enhancement and Disease Prevention. Silver Spring, MD: John Wiley, Chapter 13, pp. 209-221, 1984
BACKGROUNDSallis JF, Haskell WL, Wood PD, Fortmann SP, Rogers T, Blair SN, Paffenbarger RS Jr. Physical activity assessment methodology in the Five-City Project. Am J Epidemiol. 1985 Jan;121(1):91-106. doi: 10.1093/oxfordjournals.aje.a113987.
PMID: 3964995BACKGROUNDSallis JF, Flora JA, Fortmann SP, Taylor CB, Maccoby N. Mediated smoking cessation programs in the Stanford Five-City Project. Addict Behav. 1985;10(4):441-3. doi: 10.1016/0306-4603(85)90043-7.
PMID: 4091078BACKGROUNDFarquhar JW, Fortmann SP, Maccoby N, Haskell WL, Williams PT, Flora JA, Taylor CB, Brown BW Jr, Solomon DS, Hulley SB. The Stanford Five-City Project: design and methods. Am J Epidemiol. 1985 Aug;122(2):323-34. doi: 10.1093/oxfordjournals.aje.a114104.
PMID: 4014215BACKGROUNDBlair SN, Haskell WL, Ho P, Paffenbarger RS Jr, Vranizan KM, Farquhar JW, Wood PD. Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments. Am J Epidemiol. 1985 Nov;122(5):794-804. doi: 10.1093/oxfordjournals.aje.a114163.
PMID: 3876763BACKGROUNDFortmann SP, Sallis JF, Magnus PM, Farquhar JW. Attitudes and practices of physicians regarding hypertension and smoking: The Stanford Five City Project. Prev Med. 1985 Jan;14(1):70-80. doi: 10.1016/0091-7435(85)90022-2.
PMID: 4034516BACKGROUNDFarquhar JW, Maccoby N, Wood PD: Education and Communication Studies. In: Holland WW, Detels R & Knox G (Eds). Oxford Textbook of Public Health0, Vol. 3. Oxford, London: Oxford University Press, pp. 207-221, 1985
BACKGROUNDJacob RG, Fortmann SP, Kraemer HC, Farquhar JW, Agras WS. Combining behavioral treatments to reduce blood pressure. A controlled outcome study. Behav Modif. 1985 Jan;9(1):32-53. doi: 10.1177/01454455850091003. No abstract available.
PMID: 3977813BACKGROUNDSallis JF, Haskell WL, Wood PD, Fortmann SP, Vranizan KM. Vigorous physical activity and cardiovascular risk factors in young adults. J Chronic Dis. 1986;39(2):115-20. doi: 10.1016/0021-9681(86)90067-6.
PMID: 3484748BACKGROUNDFortmann SP, Haskell WL, Williams PT, Varady AN, Hulley SB, Farquhar JW. Community surveillance of cardiovascular diseases in the Stanford Five-City Project. Methods and initial experience. Am J Epidemiol. 1986 Apr;123(4):656-69. doi: 10.1093/oxfordjournals.aje.a114285.
PMID: 3953544BACKGROUNDFortmann SP, Haskell WL, Williams PT. Changes in plasma high density lipoprotein cholesterol after changes in cigarette use. Am J Epidemiol. 1986 Oct;124(4):706-10. doi: 10.1093/oxfordjournals.aje.a114445. No abstract available.
PMID: 3752064BACKGROUNDSallis JF, Hill RD, Killen JD, Telch MJ, Flora JA, Girard J, Taylor CB, Fortmann SP. Efficacy of self-help behavior modification materials in smoking cessation. Am J Prev Med. 1986 Nov-Dec;2(6):342-4.
PMID: 3453200BACKGROUNDSallis JF, Haskell WL, Fortmann SP, Wood PD, Vranizan KM. Moderate-intensity physical activity and cardiovascular risk factors: the Stanford Five-City Project. Prev Med. 1986 Nov;15(6):561-8. doi: 10.1016/0091-7435(86)90061-7.
PMID: 3797388BACKGROUNDSallis JF, Hill RD, Fortmann SP, Flora JA. Health behavior change at the worksite: cardiovascular risk reduction. Prog Behav Modif. 1986;20:161-97. doi: 10.1016/b978-0-12-535620-6.50009-3. No abstract available.
PMID: 3517827BACKGROUNDSallis JF, Haskell WL, Fortmann SP, Vranizan KM, Taylor CB, Solomon DS. Predictors of adoption and maintenance of physical activity in a community sample. Prev Med. 1986 Jul;15(4):331-41. doi: 10.1016/0091-7435(86)90001-0.
PMID: 3763558BACKGROUNDChafee SH, Roser C: Involvement and the Consistency of Knowledge, Attitudes, and Behaviors. Commun Res, 13:373-399, 1986
BACKGROUNDKing AC, Flora JA, Fortmann SP, Taylor CB. Smokers' challenge: immediate and long-term findings of a community smoking cessation contest. Am J Public Health. 1987 Oct;77(10):1340-1. doi: 10.2105/ajph.77.10.1340.
PMID: 3631371BACKGROUNDTuomilehto J, Kuulasmaa K, Torppa J. WHO MONICA Project: geographic variation in mortality from cardiovascular diseases. Baseline data on selected population characteristics and cardiovascular mortality. World Health Stat Q. 1987;40(2):171-84. No abstract available. English, French.
PMID: 3617777BACKGROUNDMaron DJ, Fortmann SP. Nicotine yield and measures of cigarette smoke exposure in a large population: are lower-yield cigarettes safer? Am J Public Health. 1987 May;77(5):546-9. doi: 10.2105/ajph.77.5.546.
PMID: 3565645BACKGROUNDAltman DG, Flora JA, Fortmann SP, Farquhar JW. The cost-effectiveness of three smoking cessation programs. Am J Public Health. 1987 Feb;77(2):162-5. doi: 10.2105/ajph.77.2.162.
PMID: 3099586BACKGROUNDWilliams PT, Karlin S, Farquhar JW. Permutation analyses of familial association arrays for lipoprotein concentrations in families of the Stanford Five City Project. Am J Epidemiol. 1987 Dec;126(6):1126-40. doi: 10.1093/oxfordjournals.aje.a114751.
PMID: 3687922BACKGROUNDKing AC, Saylor KE, Foster S, Killen JD, Telch MJ, Farquhar JW, Flora JA. Promoting dietary change in adolescents: a school-based approach for modifying and maintaining healthful behavior. Am J Prev Med. 1988 Mar-Apr;4(2):68-74.
PMID: 3395493BACKGROUNDFlora JA, Farquhar JW. Methods of message design: experiences from the Stanford Five City Project. Scand J Prim Health Care Suppl. 1988;1:39-47.
PMID: 3227201BACKGROUNDFarquhar JW, Fortmann SP, Flora JA, Taylor CB, Haskell WL, Williams PT, Maccoby N, Wood PD. Effects of communitywide education on cardiovascular disease risk factors. The Stanford Five-City Project. JAMA. 1990 Jul 18;264(3):359-65.
PMID: 2362332BACKGROUNDFortmann SP, Winkleby MA, Flora JA, Haskell WL, Taylor CB. Effect of long-term community health education on blood pressure and hypertension control. The Stanford Five-City Project. Am J Epidemiol. 1990 Oct;132(4):629-46. doi: 10.1093/oxfordjournals.aje.a115705.
PMID: 2403104BACKGROUNDAlbright CL, Flora JA, Fortmann SP. Restaurant menu labeling: impact of nutrition information on entree sales and patron attitudes. Health Educ Q. 1990 Summer;17(2):157-67. doi: 10.1177/109019819001700203.
PMID: 2347693BACKGROUNDWinkleby MA, Fortmann SP, Barrett DC. Social class disparities in risk factors for disease: eight-year prevalence patterns by level of education. Prev Med. 1990 Jan;19(1):1-12. doi: 10.1016/0091-7435(90)90001-z.
PMID: 2320553BACKGROUNDFrank E, Winkleby MA, Fortmann SP, Rockhill B, Farquhar JW. Improved cholesterol-related knowledge and behavior and plasma cholesterol levels in adults during the 1980s. JAMA. 1992 Sep 23-30;268(12):1566-72.
PMID: 1518111BACKGROUNDTaylor CB, Fortmann SP, Flora J, Kayman S, Barrett DC, Jatulis D, Farquhar JW. Effect of long-term community health education on body mass index. The Stanford Five-City Project. Am J Epidemiol. 1991 Aug 1;134(3):235-49. doi: 10.1093/oxfordjournals.aje.a116077.
PMID: 1877583BACKGROUNDFarquhar JW. The Stanford Cardiovascular Disease Prevention Programs. Ann N Y Acad Sci. 1991;623:327-31. doi: 10.1111/j.1749-6632.1991.tb43742.x. No abstract available.
PMID: 2042841BACKGROUNDWinkleby MA, Fortmann SP, Rockhill B. Trends in cardiovascular disease risk factors by educational level: the Stanford Five-City Project. Prev Med. 1992 Sep;21(5):592-601. doi: 10.1016/0091-7435(92)90067-r.
PMID: 1438109BACKGROUNDHyman DJ, Barrett DC, Fortmann SP. Effect of minor illness on serum cholesterol level. Am J Prev Med. 1992 Mar-Apr;8(2):100-3.
PMID: 1599716BACKGROUNDWinkleby MA, Jatulis DE, Frank E, Fortmann SP. Socioeconomic status and health: how education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health. 1992 Jun;82(6):816-20. doi: 10.2105/ajph.82.6.816.
PMID: 1585961BACKGROUNDJackson C, Jatulis DE, Fortmann SP. The Behavioral Risk Factor Survey and the Stanford Five-City Project Survey: a comparison of cardiovascular risk behavior estimates. Am J Public Health. 1992 Mar;82(3):412-6. doi: 10.2105/ajph.82.3.412.
PMID: 1536358BACKGROUNDJackson C, Winkleby MA, Flora JA, Fortmann SP. Use of educational resources for cardiovascular risk reduction in the Stanford Five-City Project. Am J Prev Med. 1991 Mar-Apr;7(2):82-8.
PMID: 1910892BACKGROUNDWilliams JE, Flora JA. Health behavior segmentation and campaign planning to reduce cardiovascular disease risk among Hispanics. Health Educ Q. 1995 Feb;22(1):36-48. doi: 10.1177/109019819502200105.
PMID: 7721600BACKGROUNDTaylor CB, Jatulis DE, Winkleby MA, Rockhill BJ, Kraemer HC. Effects of life-style on body mass index change. Epidemiology. 1994 Nov;5(6):599-603. doi: 10.1097/00001648-199411000-00007.
PMID: 7841241BACKGROUNDDavis SK, Winkleby MA, Farquhar JW. Increasing disparity in knowledge of cardiovascular disease risk factors and risk-reduction strategies by socioeconomic status: implications for policymakers. Am J Prev Med. 1995 Sep-Oct;11(5):318-23.
PMID: 8573362BACKGROUNDFortmann SP, Flora JA, Winkleby MA, Schooler C, Taylor CB, Farquhar JW. Community intervention trials: reflections on the Stanford Five-City Project Experience. Am J Epidemiol. 1995 Sep 15;142(6):576-86. doi: 10.1093/oxfordjournals.aje.a117678.
PMID: 7653465BACKGROUNDFrank E, Winkleby M, Fortmann SP, Rockhill B, Farquhar JW. Improvements in cholesterol-related knowledge and behavior and plasma cholesterol levels in youths during the 1980s. Am J Prev Med. 1993 May-Jun;9(3):168-74.
PMID: 8347368BACKGROUNDFrank E, Winkleby M, Fortmann SP, Farquhar JW. Cardiovascular disease risk factors: improvements in knowledge and behavior in the 1980s. Am J Public Health. 1993 Apr;83(4):590-3. doi: 10.2105/ajph.83.4.590.
PMID: 8460744BACKGROUNDWinkleby MA, Schooler C, Kraemer HC, Lin J, Fortmann SP. Hispanic versus white smoking patterns by sex and level of education. Am J Epidemiol. 1995 Aug 15;142(4):410-8. doi: 10.1093/oxfordjournals.aje.a117649.
PMID: 7625406BACKGROUNDTaylor CB, Jatulis DE, Fortmann SP, Kraemer HC. Weight variability effects: a prospective analysis from the Stanford Five-City Project. Am J Epidemiol. 1995 Mar 1;141(5):461-5. doi: 10.1093/oxfordjournals.aje.a117448.
PMID: 7879790BACKGROUNDWinkleby MA, Albright CL, Howard-Pitney B, Lin J, Fortmann SP. Hispanic/white differences in dietary fat intake among low educated adults and children. Prev Med. 1994 Jul;23(4):465-73. doi: 10.1006/pmed.1994.1064.
PMID: 7971874BACKGROUNDYoung DR, Haskell WL, Jatulis DE, Fortmann SP. Associations between changes in physical activity and risk factors for coronary heart disease in a community-based sample of men and women: the Stanford Five-City Project. Am J Epidemiol. 1993 Aug 15;138(4):205-16. doi: 10.1093/oxfordjournals.aje.a116849.
PMID: 8356962BACKGROUNDWinkleby MA, Fortmann SP, Rockhill B. Health-related risk factors in a sample of Hispanics and whites matched on sociodemographic characteristics. The Stanford Five-City Project. Am J Epidemiol. 1993 Jun 15;137(12):1365-75. doi: 10.1093/oxfordjournals.aje.a116646.
PMID: 8333418BACKGROUNDWilliams EL, Winkleby MA, Fortmann SP. Changes in coronary heart disease risk factors in the 1980s: evidence of a male-female crossover effect with age. Am J Epidemiol. 1993 May 15;137(10):1056-67. doi: 10.1093/oxfordjournals.aje.a116609.
PMID: 8317435BACKGROUNDFortmann SP, Taylor CB, Flora JA, Winkleby MA. Effect of community health education on plasma cholesterol levels and diet: the Stanford Five-City Project. Am J Epidemiol. 1993 May 15;137(10):1039-55. doi: 10.1093/oxfordjournals.aje.a116608.
PMID: 8317434BACKGROUNDFortmann SP, Taylor CB, Flora JA, Jatulis DE. Changes in adult cigarette smoking prevalence after 5 years of community health education: the Stanford Five-City Project. Am J Epidemiol. 1993 Jan 1;137(1):82-96. doi: 10.1093/oxfordjournals.aje.a116605.
PMID: 8434576BACKGROUNDFarquhar JW, Fortmann SP, Wood PD, Haskell WL: Community Studies of Cardiovascular Disease Prevention. In: Kaplan NM, Stamler J (Eds). Prevention of Coronary Heart Disease. Philadelphia: W.B. Saunders, 170-181, 1983
BACKGROUNDFortmann SP, Haskell WL, Vranizan K, Brown BW, Farquhar JW. The association of blood pressure and dietary alcohol: differences by age, sex, and estrogen use. Am J Epidemiol. 1983 Oct;118(4):497-507. doi: 10.1093/oxfordjournals.aje.a113655.
PMID: 6637977BACKGROUNDFarquhar JW, Maccoby N, Solomon DS: Community Applications of Behavioral Medicine. In: Gentry WD (Ed), Handbook of Behavioral Medicine, The Guilford Press, NY, 437-478, 1984
BACKGROUNDKing AC, Kiernan M, Ahn DK, Wilcox S. The effects of marital transitions on changes in physical activity: results from a 10-year community study. Ann Behav Med. 1998 Spring;20(2):64-9. doi: 10.1007/BF02884450.
PMID: 9989310BACKGROUNDGreeno CG, Jackson C, Williams EL, Fortmann SP. The effect of perceived control over eating on the life satisfaction of women and men: results from a community sample. Int J Eat Disord. 1998 Dec;24(4):415-9. doi: 10.1002/(sici)1098-108x(199812)24:43.0.co;2-9.
PMID: 9813766BACKGROUNDDavis SK, Ahn DK, Fortmann SP, Farquhar JW. Determinants of cholesterol screening and treatment patterns. Insights for decision-makers. Am J Prev Med. 1998 Oct;15(3):178-86. doi: 10.1016/s0749-3797(98)00047-6.
PMID: 9791635BACKGROUNDRibisl KM, Winkleby MA, Fortmann SP, Flora JA. The interplay of socioeconomic status and ethnicity on Hispanic and white men's cardiovascular disease risk and health communication patterns. Health Educ Res. 1998 Sep;13(3):407-17. doi: 10.1093/her/13.3.407.
PMID: 10186451BACKGROUNDWinkleby MA, Feldman HA, Murray DM. Joint analysis of three U.S. community intervention trials for reduction of cardiovascular disease risk. J Clin Epidemiol. 1997 Jun;50(6):645-58. doi: 10.1016/s0895-4356(97)00020-6.
PMID: 9250263BACKGROUNDWild SH, Fortmann SP, Marcovina SM. A prospective case-control study of lipoprotein(a) levels and apo(a) size and risk of coronary heart disease in Stanford Five-City Project participants. Arterioscler Thromb Vasc Biol. 1997 Feb;17(2):239-45. doi: 10.1161/01.atv.17.2.239.
PMID: 9081676BACKGROUNDWinkleby MA, Taylor CB, Jatulis D, Fortmann SP. The long-term effects of a cardiovascular disease prevention trial: the Stanford Five-City Project. Am J Public Health. 1996 Dec;86(12):1773-9. doi: 10.2105/ajph.86.12.1773.
PMID: 9003136BACKGROUNDOka RK, Fortmann SP, Varady AN. Differences in treatment of acute myocardial infarction by sex, age, and other factors (the Stanford Five-City Project). Am J Cardiol. 1996 Oct 15;78(8):861-5. doi: 10.1016/s0002-9149(96)00457-2.
PMID: 8888655BACKGROUNDGardner CD, Fortmann SP, Krauss RM. Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. JAMA. 1996 Sep 18;276(11):875-81.
PMID: 8782636BACKGROUNDSchooler C, Sundar SS, Flora J. Effects of the Stanford Five-City Project Media Advocacy Program. Health Educ Q. 1996 Aug;23(3):346-64. doi: 10.1177/109019819602300306.
PMID: 8841819BACKGROUNDYoung DR, Haskell WL, Taylor CB, Fortmann SP. Effect of community health education on physical activity knowledge, attitudes, and behavior. The Stanford Five-City Project. Am J Epidemiol. 1996 Aug 1;144(3):264-74. doi: 10.1093/oxfordjournals.aje.a008921.
PMID: 8686695BACKGROUNDWinkleby MA, Gardner CD, Taylor CB. The influence of gender and socioeconomic factors on Hispanic/white differences in body mass index. Prev Med. 1996 Mar-Apr;25(2):203-11. doi: 10.1006/pmed.1996.0047.
PMID: 8860286BACKGROUNDWinkleby MA, Kraemer H, Lin J, Jatulis D, Fortmann SP. Sociodemographic influences on Hispanic-white differences in blood pressure. Public Health Rep. 1996;111 Suppl 2(Suppl 2):30-2.
PMID: 8898768BACKGROUNDWild SH, Laws A, Fortmann SP, Varady AN, Byrne CD. Mortality from coronary heart disease and stroke for six ethnic groups in California, 1985 to 1990. Ann Epidemiol. 1995 Nov;5(6):432-9. doi: 10.1016/1047-2797(95)00058-5.
PMID: 8680605BACKGROUNDFortmann SP, Varady AN. Effects of a community-wide health education program on cardiovascular disease morbidity and mortality: the Stanford Five-City Project. Am J Epidemiol. 2000 Aug 15;152(4):316-23. doi: 10.1093/aje/152.4.316.
PMID: 10968376BACKGROUNDGardner CD, Tribble DL, Young DR, Ahn D, Fortmann SP. Associations of HDL, HDL(2), and HDL(3) cholesterol and apolipoproteins A-I and B with lifestyle factors in healthy women and men: the Stanford Five City Project. Prev Med. 2000 Oct;31(4):346-56. doi: 10.1006/pmed.2000.0716.
PMID: 11006059BACKGROUNDGardner CD, Tribble DL, Young DR, Ahn D, Fortmann SP. Population frequency distributions of HDL, HDL(2), and HDL(3) cholesterol and apolipoproteins A-I and B in healthy men and women and associations with age, gender, hormonal status, and sex hormone use: the Stanford Five City Project. Prev Med. 2000 Oct;31(4):335-45. doi: 10.1006/pmed.2000.0715.
PMID: 11006058BACKGROUNDRimal RN. Closing the knowledge-behavior gap in health promotion: the mediating role of self-efficacy. Health Commun. 2000;12(3):219-37. doi: 10.1207/S15327027HC1203_01.
PMID: 10938914BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
John W Farquhar
Stanford University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 25, 2000
First Posted
May 26, 2000
Study Start
July 1, 1978
Primary Completion
July 1, 1994
Study Completion
July 1, 1994
Last Updated
February 16, 2021
Record last verified: 2021-02