NCT00005138

Brief Summary

To continue a longitudinal study of blood pressure and blood pressure correlates in a population of 1,140 young adults, first seen in 1973 as adolescents, aged 14-19 years.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jun 1976

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 1976

Completed
13 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 1989

Completed
11 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
Last Updated

May 13, 2016

Status Verified

May 1, 2000

First QC Date

May 25, 2000

Last Update Submit

May 12, 2016

Conditions

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (20)

  • Kotchen JM. Effect of relative weight on familial blood pressure aggregations. Am J Epidemiol. 1977 Mar;105(3):214-22. doi: 10.1093/oxfordjournals.aje.a112377.

    PMID: 848475BACKGROUND
  • Kotchen JM, Kotchen TA. Geographic effect on racial blood pressure differences in adolescents. J Chronic Dis. 1978;31(9-10):581-6. doi: 10.1016/0021-9681(78)90018-8. No abstract available.

    PMID: 744788BACKGROUND
  • Kotchen JM, Kotchen TA, Cottrill CM, Guthrie GP Jr, Somes G. Blood pressures of young mothers and their first children 3-6 years following hypertension during pregnancy. J Chronic Dis. 1979;32(9-10):653-9. doi: 10.1016/0021-9681(79)90095-x. No abstract available.

    PMID: 489705BACKGROUND
  • Kotchen TA, Kotchen JM, Guthrie GP Jr, Cottrill CM. Plasma renin activity, reactivity, concentration and substrate following hypertension during pregnancy. Effect of oral contraceptive agents. Hypertension. 1979 Jul-Aug;1(4):355-61. doi: 10.1161/01.hyp.1.4.355.

    PMID: 396239BACKGROUND
  • Cottrill CM, Kotchen JM, Guthrie G, Kotchen T. Cardiovascular responses to exercise following adolescent hypertensive pregnancy. J Adolesc Health Care. 1980 Dec;1(2):91-5. doi: 10.1016/s0197-0070(80)80031-3.

    PMID: 7298484BACKGROUND
  • Kotchen TA, Havlik RJ. High blood pressure in the young. Ann Intern Med. 1980 Feb;92(2 Pt 1):254-5. No abstract available.

    PMID: 7352733BACKGROUND
  • Kotchen TA, Guthrie GP Jr. Renin-angiotensin-aldosterone and hypertension. Endocr Rev. 1980 Winter;1(1):78-99. doi: 10.1210/edrv-1-1-78. No abstract available.

    PMID: 6112143BACKGROUND
  • Kotchen TA, Havlik RJ. High blood pressure in the young symposium. Hypertension. 1980 Jul-Aug;2(4 Pt 2):I134-5. doi: 10.1161/01.hyp.2.4_pt_2.i134. No abstract available.

    PMID: 7399634BACKGROUND
  • Kotchen JM, Kotchen TA, Guthrie GP Jr, Cottrill CM, McKean HE. Correlates of adolescent blood pressure at five-year follow-up. Hypertension. 1980 Jul-Aug;2(4 Pt 2):124-9.

    PMID: 7399644BACKGROUND
  • Kotchen TA, Kotchen JM: Clinical Approaches to High Blood Pressure in the Young. Cardiovasc Rev & Reports, 1:53-57, 1980

    BACKGROUND
  • Kotchen JM, Kotchen TA: Correlates of High Blood Pressure in Adolescents. In: High Blood Pressure in the Young and Old. Proceedings of the Sixth Hahnemann International Symposium. Onesti G, Kim K (Eds), Grune & Stratton, p 173-182, 1981

    BACKGROUND
  • Kotchen TA, Guthrie GP Jr, McKean H, Kotchen JM. Adrenergic responsiveness in prehypertensive subjects. Circulation. 1982 Feb;65(2):285-90. doi: 10.1161/01.cir.65.2.285.

    PMID: 7032747BACKGROUND
  • Kotchen TA, Guthrie GP Jr, Cottrill CM, McKean HE, Kotchen JM. Low renin-aldosterone in "prehypertensive" young adults. J Clin Endocrinol Metab. 1982 Apr;54(4):808-14. doi: 10.1210/jcem-54-4-808.

    PMID: 7037816BACKGROUND
  • Kotchen JM, McKean HE, Kotchen TA. Blood pressure of young mothers and their children after hypertension in adolescent pregnancy: six- to nine-year follow-up. Am J Epidemiol. 1982 Jun;115(6):861-7. doi: 10.1093/oxfordjournals.aje.a113373.

    PMID: 7091144BACKGROUND
  • Cottrill CM, Kotchen JM, Guthrie GP Jr, Kotchen TA. Low renin in young mothers and their children following hypertension in pregnancy. Hypertension. 1982 May-Jun;4(3 Pt 2):119-24.

    PMID: 7040236BACKGROUND
  • Kotchen JM, McKean HE, Kotchen TA. Blood pressure trends with aging. Hypertension. 1982 Sep-Oct;4(5 Pt 2):III128-34. doi: 10.1161/01.hyp.4.5_pt_2.iii128.

    PMID: 7049927BACKGROUND
  • Guthrie GP Jr, Kotchen TA, Kotchen JM. Suppression of adrenal mineralocorticoid production in prehypertensive young adult men. J Clin Endocrinol Metab. 1983 Jan;56(1):87-92. doi: 10.1210/jcem-56-1-87.

    PMID: 6292257BACKGROUND
  • Johnson GL, Kotchen JM, McKean HE, Cottrill CM, Kotchen TA. Blood pressure related echocardiographic changes in adolescents and young adults. Am Heart J. 1983 Jan;105(1):113-8. doi: 10.1016/0002-8703(83)90287-9.

    PMID: 6217735BACKGROUND
  • Kotchen JM, McKean HE, Neill M, Kotchen TA. Blood pressure trends associated with changes in height and weight from early adolescence to young adulthood. J Clin Epidemiol. 1989;42(8):735-41. doi: 10.1016/0895-4356(89)90069-3.

    PMID: 2760664BACKGROUND
  • Kotchen TA, Kotchen JM, Guthrie GP Jr, Berk MR, Knapp CF, McFadden M. Baroreceptor sensitivity in prehypertensive young adults. Hypertension. 1989 Jun;13(6 Pt 2):878-83. doi: 10.1161/01.hyp.13.6.878.

    PMID: 2737725BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

June 1, 1976

Study Completion

June 1, 1989

Last Updated

May 13, 2016

Record last verified: 2000-05