NCT00001121

Brief Summary

The purpose of this study is to evaluate the long-term consequences of HIV-1 infections that occurred in association with known, but discouraged, high-risk behaviors in persons who have received HIV candidate vaccines or placebo in HIVNET 014. Doctors need to look at how these patients respond to HIV infection in order to develop new HIV vaccines and other treatments for HIV and AIDS. Patients who receive HIV vaccines are sometimes protected from HIV infection. More often, these patients become HIV-positive but experience a boost in their immune system that helps their bodies fight HIV. Doctors need to look at how these patients respond to HIV infection in order to develop new HIV vaccines and other treatments for HIV and AIDS.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 1999

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

November 2, 1999

Completed
1.8 years until next milestone

First Posted

Study publicly available on registry

August 31, 2001

Completed
Last Updated

September 12, 2008

Status Verified

June 1, 2003

First QC Date

November 2, 1999

Last Update Submit

September 11, 2008

Conditions

Keywords

PlacebosAIDS VaccinesFollow-Up StudiesHIV Therapeutic Vaccine

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients may be eligible for this study if they:
  • Become infected with HIV while participating in HIVNET 014, or if they are an HIV-positive partner (sexual or needle-sharing) of a HIVNET 014A participant.
  • Are able and willing to provide written informed consent.

You may not qualify if:

  • Patients will not be eligible for this study if they:
  • Have a serious psychiatric or psychological disorder that would prevent them from completing the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

San Francisco Dept of Hlth / AIDS Office

San Francisco, California, 94102, United States

Location

Denver Dept of Public Health / HIVNET

Denver, Colorado, 80204, United States

Location

Univ of Illinois Chicago / Howard Brown Hlth Ctr

Chicago, Illinois, 60612, United States

Location

Howard Brown Health Ctr / HIVNET

Chicago, Illinois, 60657, United States

Location

Fenway Community Health Ctr / HIVNET

Boston, Massachusetts, 02115, United States

Location

New York Univ Med Ctr

New York, New York, 10016, United States

Location

New York Blood Ctr

The Bronx, New York, 10456, United States

Location

Univ of Pennsylvania / HIVNET

Philadelphia, Pennsylvania, 19104, United States

Location

Mem Hosp of Rhode Island

Pawtucket, Rhode Island, 02860, United States

Location

Miriam Hosp

Providence, Rhode Island, 02906, United States

Location

Univ of Washington

Seattle, Washington, 98104, United States

Location

MeSH Terms

Conditions

HIV Infections

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Officials

  • Connie Celum

    STUDY CHAIR
  • Susan Buchbinder

    STUDY CHAIR
  • Haynes Sheppard

    STUDY CHAIR

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

November 2, 1999

First Posted

August 31, 2001

Study Start

August 1, 1999

Last Updated

September 12, 2008

Record last verified: 2003-06

Locations