NCT00000169

Brief Summary

To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda Longitudinal Study of Myopia. To investigate risk factors for the development of myopia. To conduct DNA-based studies on nearsighted children and their families.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1999

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

September 23, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 24, 1999

Completed
Last Updated

June 24, 2005

Status Verified

June 1, 2001

First QC Date

September 23, 1999

Last Update Submit

June 23, 2005

Conditions

Myopia

Eligibility Criteria

Age6 Years - 14 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Children were eligible if they were enrolled in the first through eighth grades in selected schools in Eutaw, Alabama; Houston, Texas; Orinda, California; or Irvine, California in the 1997-98 academic year and in the first grade only in Eutaw, Houston, and Irvine in the 1998-99 academic year.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (3)

West Alabama Health Services, Inc.

Eutaw, Alabama, 35462, United States

RECRUITING

Southern California College of Optometry

Fullerton, California, 92831, United States

RECRUITING

University of Houston, College of Optometry

Houston, Texas, 77204-2020, United States

RECRUITING

Related Publications (16)

  • Mutti DO, Zadnik K, Adams AJ. A video technique for phakometry of the human crystalline lens. Invest Ophthalmol Vis Sci. 1992 Apr;33(5):1771-82.

    PMID: 1559777BACKGROUND

  • Zadnik K, Mutti DO, Adams AJ. The repeatability of measurement of the ocular components. Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2325-33.

    PMID: 1607244BACKGROUND

  • Walline JJ, Zadnik K, Mutti DO. Validity of surveys reporting myopia, astigmatism, and presbyopia. Optom Vis Sci. 1996 Jun;73(6):376-81. doi: 10.1097/00006324-199606000-00004.

    PMID: 8807648BACKGROUND

  • Zadnik K, Mutti DO, Friedman NE, Adams AJ. Initial cross-sectional results from the Orinda Longitudinal Study of Myopia. Optom Vis Sci. 1993 Sep;70(9):750-8. doi: 10.1097/00006324-199309000-00012.

    PMID: 8233371BACKGROUND

  • Zadnik K, Satariano WA, Mutti DO, Sholtz RI, Adams AJ. The effect of parental history of myopia on children's eye size. JAMA. 1994 May 4;271(17):1323-7.

    PMID: 8158816BACKGROUND

  • Zadnik K, Friedman NE, Mutti DO. Repeatability of corneal topography: the "corneal field". J Refract Surg. 1995 Mar-Apr;11(2):119-25. doi: 10.3928/1081-597X-19950301-12.

    PMID: 7634141BACKGROUND

  • Mutti DO, Zadnik K, Adams AJ. The equivalent refractive index of the crystalline lens in childhood. Vision Res. 1995 Jun;35(11):1565-73. doi: 10.1016/0042-6989(94)00262-k.

    PMID: 7667914BACKGROUND

  • Zadnik K, Mutti DO, Fusaro RE, Adams AJ. Longitudinal evidence of crystalline lens thinning in children. Invest Ophthalmol Vis Sci. 1995 Jul;36(8):1581-7.

    PMID: 7601639BACKGROUND

  • Friedman NE, Zadnik K, Mutti DO, Fusaro RE. Quantifying corneal toricity from videokeratography with Fourier analysis. J Refract Surg. 1996 Jan-Feb;12(1):108-13. doi: 10.3928/1081-597X-19960101-20.

    PMID: 8963798BACKGROUND

  • Friedman NE, Mutti DO, Zadnik K. Corneal changes in schoolchildren. Optom Vis Sci. 1996 Aug;73(8):552-7. doi: 10.1097/00006324-199608000-00006.

    PMID: 8869987BACKGROUND

  • Mutti DO, Zadnik K, Fusaro RE, Friedman NE, Sholtz RI, Adams AJ. Optical and structural development of the crystalline lens in childhood. Invest Ophthalmol Vis Sci. 1998 Jan;39(1):120-33.

    PMID: 9430553BACKGROUND

  • Kleinstein RN, Mutti DO, Manny RE, Shin JA, Zadnik K. Cycloplegia in African-American children. Optom Vis Sci. 1999 Feb;76(2):102-7. doi: 10.1097/00006324-199902000-00017.

    PMID: 10082056BACKGROUND

  • Shin JA, Manny RE, Kleinstein RN, Mutti DO, Zadnik K. Short-term repeatability of hand-held keratometry measurements. Optom Vis Sci. 1999 Apr;76(4):247-53. doi: 10.1097/00006324-199904000-00029.

    PMID: 10333188BACKGROUND

  • Zadnik K, Mutti DO, Kim HS, Jones LA, Qiu PH, Moeschberger ML. Tonic accommodation, age, and refractive error in children. Invest Ophthalmol Vis Sci. 1999 May;40(6):1050-60.

    PMID: 10235538BACKGROUND

  • Zadnik K, Mutti DO, Friedman NE, Qualley PA, Jones LA, Qui P, Kim HS, Hsu JC, Moeschberger ML. Ocular predictors of the onset of juvenile myopia. Invest Ophthalmol Vis Sci. 1999 Aug;40(9):1936-43.

    PMID: 10440246BACKGROUND

  • Kleinstein RN, Mutti DO, Sinnott LT, Jones-Jordan LA, Cotter SA, Manny RE, Twelker JD, Zadnik K; Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Group. Uncorrected Refractive Error and Distance Visual Acuity in Children Aged 6 to 14 Years. Optom Vis Sci. 2021 Jan 1;98(1):3-12. doi: 10.1097/OPX.0000000000001630.

    PMID: 33394925DERIVED

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Central Study Contacts

Lisa A. Jones, Ph.D.

CONTACT

1-614-292-7097jones.809@osu.edu

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

September 23, 1999

First Posted

September 24, 1999

Study Start

April 1, 1999

Last Updated

June 24, 2005

Record last verified: 2001-06

Locations

US(3)