NCT00000126

Brief Summary

To follow all patients enrolled in the original Ischemic Optic Neuropathy Decompression Trial (IONDT) to determine (1) the incidence of non-arteritic ischemic optic neuropathy (NAION) in the second eye, (2) changes in visual acuity over time in both the study and second eye, and (3) other aspects of the natural history of NAION.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

24 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 1994

Completed
5 years until next milestone

First Submitted

Initial submission to the registry

September 23, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 24, 1999

Completed
Last Updated

May 26, 2006

Status Verified

October 1, 2003

First QC Date

September 23, 1999

Last Update Submit

May 25, 2006

Conditions

Keywords

Non-arteritic Ischemic Optic Neuropathy

Interventions

SurgeryPROCEDURE

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
All living patients from the 420 patients originally enrolled in the IONDT have been asked to participate in the IONDT Followup Study. No new patients are being recruited.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (24)

Doheny Eye Institute, University of Southern California

Los Angeles, California, United States

Location

Jules Stein Eye Institute

Los Angeles, California, United States

Location

Department of Ophthalmology, University of California, San Francisco

San Francisco, California, United States

Location

Department of Ophthalmology, University of Florida

Gainesville, Florida, United States

Location

Emory Eye Center, Emory University

Atlanta, Georgia, United States

Location

Department of Ophthalmology, University of Illinois

Chicago, Illinois, United States

Location

Department of Ophthalmology, University of Kentucky

Lexington, Kentucky, United States

Location

University of Maryland

Baltimore, Maryland, United States

Location

W.K. Kellogg Eye Center, University of Michigan

Ann Arbor, Michigan, United States

Location

Department of Ophthalmology, Michigan State University

East Lansing, Michigan, United States

Location

William Beaumont Eye Institute, William Beaumont Hospital

Royal Oak, Michigan, United States

Location

Mayo Clinic

Rochester, Minnesota, United States

Location

Mason Institute of Ophthalmology, University of Missouri - Columbia

Columbia, Missouri, United States

Location

St. Louis University, Anheuser-Busch Eye Institute

St Louis, Missouri, United States

Location

SUNY Health Science Center, Department of Neurology

Syracuse, New York, United States

Location

Carolinas Medical Center

Charlotte, North Carolina, United States

Location

The Cleveland Clinic Foundation

Cleveland, Ohio, United States

Location

Allegheny General Hospital

Pittsburgh, Pennsylvania, United States

Location

University of South Carolina, Department of Ophthalmology

Columbia, South Carolina, United States

Location

University of Texas

Houston, Texas, United States

Location

University of Utah, Department of Ophthalmology

Salt Lake City, Utah, United States

Location

University of Virginia, Department of Ophthalmology

Charlottesville, Virginia, United States

Location

Medical College of Virginia, Department of Neurology

Richmond, Virginia, United States

Location

West Virginia University, Department of Neurology

Morgantown, West Virginia, United States

Location

MeSH Terms

Conditions

Optic Neuropathy, Ischemic

Interventions

Surgical Procedures, Operative

Condition Hierarchy (Ancestors)

Optic Nerve DiseasesCranial Nerve DiseasesNervous System DiseasesEye DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
observational
Time Perspective
OTHER
Sponsor Type
NIH

Study Record Dates

First Submitted

September 23, 1999

First Posted

September 24, 1999

Study Start

October 1, 1994

Last Updated

May 26, 2006

Record last verified: 2003-10

Locations