Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

0.0%

0 terminated/withdrawn out of 16 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

25%

4 trials in Phase 3/4

Results Transparency

33%

5 of 15 completed trials have results

Key Signals

1 recruiting5 with results

Enrollment Performance

Analytics

Phase 1
10(62.5%)
Phase 3
4(25.0%)
Phase 2
2(12.5%)
16Total
Phase 1(10)
Phase 3(4)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT06794541Phase 2Recruiting

A Study to Evaluate the Safety and Tolerability of Eravacycline in Pediatric Patients Aged 8 to 17 With Complicated Intra-abdominal Infections (cIAI)

Role: lead

NCT01978938Phase 3Completed

Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections

Role: lead

NCT01844856Phase 3Completed

Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Complicated Intra-abdominal Infections

Role: lead

NCT02784704Phase 3Completed

Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal Infections

Role: lead

NCT03032510Phase 3Completed

Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections

Role: lead

NCT01265784Phase 2Completed

Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections

Role: lead

NCT01941446Phase 1Completed

A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization

Role: lead

NCT03691584Phase 1Completed

Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers

Role: lead

NCT02135276Phase 1Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With End Stage Renal Disease and Healthy Subjects

Role: lead

NCT03450187Phase 1Completed

A Phase 1 TP-271 Oral PK Multiple Ascending Dose Study

Role: lead

NCT02135302Phase 1Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects

Role: lead

NCT01989949Phase 1Completed

Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women

Role: lead

NCT03234738Phase 1Completed

A Phase 1 Safety and PK Study of IV TP-271

Role: lead

NCT02724085Phase 1Completed

A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271

Role: lead

NCT03024034Phase 1Completed

A Phase 1 TP-271 Oral PK Single Ascending Dose Study

Role: lead

NCT03696550Phase 1Completed

A Safety and PK Study of IV Eravacycline

Role: lead

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