Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

16.8%

70 terminated/withdrawn out of 416 trials

Success Rate

79.9%

-6.7% vs industry average

Late-Stage Pipeline

36%

149 trials in Phase 3/4

Results Transparency

53%

146 of 278 completed trials have results

Key Signals

32 recruiting146 with results51 terminated19 withdrawn

Enrollment Performance

Analytics

Phase 2
189(50.9%)
Phase 3
148(39.9%)
N/A
22(5.9%)
Phase 1
11(3.0%)
Phase 4
1(0.3%)
371Total
Phase 2(189)
Phase 3(148)
N/A(22)
Phase 1(11)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (416)

Showing 20 of 416 trials
NCT03939481Active Not Recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

Role: lead

NCT00310180Phase 3Active Not Recruiting

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Role: collaborator

NCT00003641Phase 3Completed

High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

Role: collaborator

NCT04071457Phase 3Active Not Recruiting

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Role: lead

NCT07498205Phase 4Not Yet Recruiting

Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts

Role: lead

NCT04511013Phase 2Recruiting

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

Role: lead

NCT07278739Not ApplicableRecruiting

Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams

Role: lead

NCT06771739Not ApplicableRecruiting

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

Role: collaborator

NCT07802626Phase 3Not Yet Recruiting

Adding Capivasertib to Standard Treatment in HR Positive, HER2 Negative Metastatic Breast Cancer Based on ctDNA Testing

Role: lead

NCT04315324Phase 1Active Not Recruiting

Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

Role: lead

NCT00070564Phase 3Active Not Recruiting

S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer

Role: lead

NCT00066690Phase 3Completed

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Role: collaborator

NCT04205968Phase 2Recruiting

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Role: lead

NCT06773936Phase 2Enrolling By Invitation

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Role: lead

NCT07062354Phase 2Enrolling By Invitation

Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer

Role: lead

NCT00265850Phase 3Completed

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Role: collaborator

NCT06205485Phase 3Recruiting

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Role: collaborator

NCT06592924Phase 3Recruiting

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Role: collaborator

NCT06686771Phase 3Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

Role: collaborator

NCT05451004Phase 3Recruiting

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

Role: collaborator