Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

3.4%

2 terminated/withdrawn out of 59 trials

Success Rate

93.5%

+7.0% vs industry average

Late-Stage Pipeline

20%

12 trials in Phase 3/4

Results Transparency

7%

2 of 29 completed trials have results

Key Signals

11 recruiting2 with results

Enrollment Performance

Analytics

Phase 2
20(45.5%)
Phase 3
9(20.5%)
Phase 1
7(15.9%)
N/A
4(9.1%)
Phase 4
3(6.8%)
Early Phase 1
1(2.3%)
44Total
Phase 2(20)
Phase 3(9)
Phase 1(7)
N/A(4)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (59)

Showing 20 of 59 trials
NCT05085249Completed

Improving Goal Directed Medical Therapy for Device Clinic Patients With Reduced EF at UOHI: a QI Initiative (VIGILANT)

Role: collaborator

NCT07722312Phase 1Not Yet Recruiting

S243249 Monotherapy in Patients With Relapsed or Refractory Acute Leukemia With a KMT2A or NUP98 Translocation or Relapsed or Refractory AML With NPM1c Mutation

Role: lead

NCT05609994Phase 1Recruiting

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

Role: collaborator

NCT03764553Phase 2Active Not Recruiting

Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Role: collaborator

NCT04307576Phase 3Recruiting

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Role: collaborator

NCT05592743Unknown

Vorasidenib Expanded Access Program

Role: lead

NCT05476796Phase 2Active Not Recruiting

Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer

Role: collaborator

NCT07719348Phase 1Not Yet Recruiting

A Study to Evaluate S241656 Alone or in Combination in Participants With Selected Myeloid Malignancies

Role: lead

NCT03020030Phase 3Active Not Recruiting

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Role: collaborator

NCT06707493Phase 2Recruiting

Ivosidenib as Post-HSCT Maintenance for AML

Role: collaborator

NCT03117751Phase 2Active Not Recruiting

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Role: collaborator

NCT06780930Phase 3Active Not Recruiting

Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation

Role: lead

NCT04489173Phase 2Completed

TAS102 in Patients With ER-positive, HER2-negative Advanced Breast Cancer

Role: collaborator

NCT05615818Phase 3Recruiting

Personalized Medicine for Advanced Biliary Cancer Patients

Role: collaborator

NCT05292664Phase 1Recruiting

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Role: collaborator

NCT05581030Phase 1Recruiting

CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

Role: collaborator

NCT05062889Phase 2Suspended

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients

Role: collaborator

NCT05184842Phase 2Recruiting

Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML

Role: collaborator

NCT06245356Phase 2Recruiting

Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer

Role: collaborator

NCT06081829Phase 2Active Not Recruiting

A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Role: lead