Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

25.0%

3 terminated/withdrawn out of 12 trials

Success Rate

72.7%

-13.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 8 completed trials have results

Key Signals

1 recruiting

Enrollment Performance

Analytics

Phase 1
11(91.7%)
Phase 2
1(8.3%)
12Total
Phase 1(11)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT07469891Phase 1Recruiting

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

Role: lead

NCT06682806Phase 2Terminated

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Role: lead

NCT06560645Phase 1Terminated

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Role: lead

NCT05665530Phase 1Completed

A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Role: lead

NCT05639751Phase 1Completed

PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation

Role: lead

NCT05538572Phase 1Completed

A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

Role: lead

NCT05107856Phase 1Terminated

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

Role: lead

NCT05159518Phase 1Completed

A Study of PRT2527 in Participants With Advanced Solid Tumors

Role: lead

NCT04089449Phase 1Completed

A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas

Role: lead

NCT03886831Phase 1Completed

A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies

Role: lead

NCT04837677Phase 1Completed

A Study of PRT1419 in Patients With Advanced Solid Tumors

Role: lead

NCT04543305Phase 1Completed

A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic Malignancies

Role: lead

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