Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

18.2%

2 terminated/withdrawn out of 11 trials

Success Rate

71.4%

-15.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

20%

1 of 5 completed trials have results

Key Signals

1 recruiting1 with results

Enrollment Performance

Analytics

Phase 2
6(54.5%)
Phase 1
5(45.5%)
11Total
Phase 2(6)
Phase 1(5)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT03349450Phase 2Completed

DPX-Survivac and Checkpoint Inhibitor in DLBCL

Role: collaborator

NCT03029403Phase 2Active Not Recruiting

Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Role: collaborator

NCT05243524Phase 2Terminated

Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer

Role: lead

NCT04920617Phase 2Recruiting

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Role: lead

NCT03836352Phase 2Active Not Recruiting

Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors

Role: lead

NCT02323230Phase 2Terminated

A Study of DPX-Survivac Vaccine Therapy in Patients With Recurrent Survivin-expressing DLBCL

Role: lead

NCT02785250Phase 1Unknown

Study of DPX-Survivac Therapy in Patients With Recurrent Ovarian Cancer

Role: lead

NCT03332576Phase 1Completed

Phase 1b Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer

Role: lead

NCT02472548Phase 1Completed

A Study to Evaluate the Safety and Reactogenicity of DPX-RSV(A), a Respiratory Syncytial Virus Vaccine

Role: collaborator

NCT01416038Phase 1Completed

Phase 1 Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer

Role: lead

NCT01095848Phase 1Completed

A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer

Role: lead

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