Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

24.6%

17 terminated/withdrawn out of 69 trials

Success Rate

71.2%

-15.3% vs industry average

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

98%

41 of 42 completed trials have results

Key Signals

4 recruiting41 with results16 terminated

Enrollment Performance

Analytics

Phase 2
37(59.7%)
Phase 1
19(30.6%)
Early Phase 1
5(8.1%)
Phase 3
1(1.6%)
62Total
Phase 2(37)
Phase 1(19)
Early Phase 1(5)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (69)

Showing 20 of 69 trials
NCT03577431Phase 1Active Not Recruiting

Liver Transplantation With Tregs at MGH

Role: collaborator

NCT03222492Phase 1Completed

Brentuximab Vedotin for Systemic Sclerosis

Role: collaborator

NCT07015996Phase 2Not Yet Recruiting

Efficacy of Tezepelumab in Peanut Oral Immunotherapy

Role: collaborator

NCT04502966Phase 2Completed

Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction

Role: collaborator

NCT04338581Phase 2Completed

Evaluation of AMG 714 for Vitiligo

Role: collaborator

NCT05017545Phase 1Active Not Recruiting

Carfilzomib and Belatacept for Desensitization

Role: collaborator

NCT05671757Phase 1Recruiting

Daratumumab in Primary Antiphospholipid Syndrome

Role: collaborator

NCT02734277Recruiting

Type 1 Diabetes Extension Study

Role: collaborator

NCT03504241Phase 1Completed

Tolerance by Engaging Antigen During Cellular Homeostasis

Role: collaborator

NCT03949855Phase 2Recruiting

Belimumab With Rituximab for Primary Membranous Nephropathy

Role: collaborator

NCT05306353Phase 2Terminated

CD40L Antagonism in Rheumatoid Arthritis (RA)

Role: collaborator

NCT04827979Phase 1Active Not Recruiting

Daratumumab and Belatacept for Desensitization

Role: collaborator

NCT04047628Phase 3Recruiting

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Role: collaborator

NCT03567707Early Phase 1Active Not Recruiting

Vaginal Microbiome Exposure and Immune Responses in C-section Infants

Role: collaborator

NCT04761822Phase 2Completed

COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations

Role: collaborator

NCT03654040Phase 1Terminated

Liver Transplantation With Tregs at UCSF

Role: collaborator

NCT03546413Completed

Follow up of LEAP Participants and Their Families

Role: collaborator

NCT02533180Phase 2Completed

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation

Role: collaborator

NCT05027815Phase 1Terminated

Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS)

Role: collaborator

NCT02743793Terminated

A Cohort Study of Operationally Tolerant Allograft Recipients

Role: collaborator