Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.8%

7 terminated/withdrawn out of 80 trials

Success Rate

87.9%

+1.4% vs industry average

Late-Stage Pipeline

16%

13 trials in Phase 3/4

Results Transparency

20%

10 of 51 completed trials have results

Key Signals

1 recruiting10 with results6 terminated

Enrollment Performance

Analytics

Phase 1
44(55.0%)
Phase 2
21(26.3%)
Phase 3
13(16.3%)
Early Phase 1
2(2.5%)
80Total
Phase 1(44)
Phase 2(21)
Phase 3(13)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (80)

Showing 20 of 80 trials
NCT03778229Phase 2Active Not Recruiting

Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib

Role: collaborator

NCT03091192Phase 3Active Not Recruiting

Savolitinib vs. Sunitinib in MET-driven PRCC.

Role: collaborator

NCT05535933Phase 2Active Not Recruiting

HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Role: lead

NCT03223376Phase 3Completed

A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line Gastric Cancer(FRUTIGA)

Role: lead

NCT05009836Phase 3Active Not Recruiting

Clinical Study on Savolitinib + Osimertinib in Treatment of EGFRm+/MET+ Locally Advanced or Metastatic NSCLC

Role: lead

NCT05509699Phase 2Completed

Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer

Role: lead

NCT04923932Phase 2Active Not Recruiting

Savolitinib for Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients

Role: lead

NCT05015608Phase 3Active Not Recruiting

Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification

Role: lead

NCT04849351Phase 2Completed

Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma

Role: lead

NCT04322539Phase 3Completed

A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer

Role: lead

NCT04716634Phase 2Completed

Efficacy and Safety of Tislelizumab in Combination With Fruquintinib in Participants With Selected Solid Tumors

Role: collaborator

NCT04923945Phase 3Completed

Savolitinib for Treating Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients

Role: lead

NCT06437353Phase 2Recruiting

Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer

Role: collaborator

NCT03251378Phase 1Completed

A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers

Role: lead

NCT03951623Phase 1Completed

The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Patients

Role: lead

NCT02857998Phase 1Completed

A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neoplasms

Role: lead

NCT05522738Phase 1Unknown

Safety and Efficacy of Fruquintinib+FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Role: collaborator

NCT05015621Phase 3Unknown

A Phase 3 Study to Evaluate Surufatinib Plus Toripalimab in the Treatment of Advanced Neuroendocrine Carcinoma

Role: lead

NCT03128164Phase 1Completed

A Study of HMPL-689 in Patients With Lymphomas Failed of Standard of Care or no Standard of Care Existed

Role: lead

NCT05842525Phase 2Unknown

Fruquintinib Plus FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Role: collaborator