Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

45.0%

9 terminated/withdrawn out of 20 trials

Success Rate

55.0%

-31.5% vs industry average

Late-Stage Pipeline

25%

5 trials in Phase 3/4

Results Transparency

118%

13 of 11 completed trials have results

Key Signals

13 with results4 withdrawn

Enrollment Performance

Analytics

Phase 2
14(70.0%)
Phase 3
5(25.0%)
Phase 1
1(5.0%)
20Total
Phase 2(14)
Phase 3(5)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (20)

Showing 20 of 20 trials
NCT01393119Phase 2Terminated

Phase II, Dose Finding Study of GTx-758

Role: lead

NCT01616758Phase 2Terminated

Phase II Study of GTx024 in Women With Metastatic Breast Cancer

Role: lead

NCT03566290Phase 2Withdrawn

Study to Assess Long-Term Safety/Tolerability of Enobosarm (GTx 024) in Stress Urinary Incontinence

Role: lead

NCT02746328Phase 2Withdrawn

Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass

Role: lead

NCT01420861Phase 2Terminated

GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer

Role: lead

NCT03508648Phase 2Withdrawn

Durability Extension Study to Assess Clinical Activity and Safety of Enobosarm (GTx-024) in Stress Urinary Incontinence

Role: lead

NCT01326312Phase 2Terminated

Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer

Role: lead

NCT00106691Phase 3Completed

Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia)

Role: lead

NCT03241342Phase 2Completed

Study to Assess Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence

Role: lead

NCT01615120Phase 2Completed

Study of the Effect of GTx-758 on Serum PSA and Testosterone in Men With Prostate Cancer

Role: lead

NCT02658448Phase 2Completed

GTx-024 as a Treatment for Stress Urinary Incontinence in Women

Role: lead

NCT02463032Phase 2Completed

Efficacy and Safety of GTx-024 in Patients With Estrogen Receptor (ER)+/Androgen Receptor (AR)+ Breast Cancer

Role: lead

NCT02368691Phase 2Terminated

Efficacy and Safety of GTx-024 in Patients With Androgen Receptor-Positive Triple Negative Breast Cancer (AR+ TNBC)

Role: lead

NCT01355497Phase 3Completed

Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum

Role: lead

NCT03264651Phase 1Completed

Enobosarm and Anastrozole in Pre-menopausal Women With High Mammographic Breast Density

Role: collaborator

NCT01355484Phase 3Completed

Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)

Role: lead

NCT00467844Phase 2Completed

Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.

Role: lead

NCT01214291Phase 3Withdrawn

Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer

Role: lead

NCT00028353Phase 2Completed

A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN)

Role: lead

NCT00129142Phase 3Completed

Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy

Role: lead

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