Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 5/100

Failure Rate

5.1%

11 terminated/withdrawn out of 217 trials

Late-Stage Pipeline

45%

98 trials in Phase 3/4

Results Transparency

124%

56 of 45 completed trials have results

Key Signals

48 recruiting56 with results11 terminated

Enrollment reporting

Analytics

Phase 3
93(42.9%)
Phase 1
50(23.0%)
Phase 2
43(19.8%)
Phase 1/2
22(10.1%)
Phase 4
5(2.3%)
Phase 2/3
4(1.8%)
217Total
Phase 3(93)
Phase 1(50)
Phase 2(43)
Phase 1/2(22)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (217)

Showing 20 of 217 trials
NCT04861259Phase 3Active Not Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Role: lead

NCT05861986Phase 4Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

Role: lead

NCT04657289Phase 3Active Not Recruiting

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Role: lead

NCT03075696Phase 1/2Active Not Recruiting

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Role: lead

NCT05269004Phase 3Active Not Recruiting

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis

Role: lead

NCT05595642Phase 3Completed

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Role: lead

NCT05797610Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Role: lead

NCT03683251Phase 3Recruiting

Extension Study for the Port Delivery System With Ranibizumab (Portal)

Role: lead

NCT06795048Phase 4Active Not Recruiting

A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

Role: lead

NCT04432584Phase 3Active Not Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

Role: lead

NCT04434092Phase 3Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

Role: lead

NCT05645692Phase 2Active Not Recruiting

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Role: lead

NCT06819891Phase 3Recruiting

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Role: lead

NCT07054190Phase 2Recruiting

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

Role: lead

NCT07223697Phase 2Active Not Recruiting

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Role: lead

NCT07416526Phase 3Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

Role: lead

NCT05181618Phase 4Active Not Recruiting

A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis

Role: lead

NCT06094010Phase 3Recruiting

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

Role: lead

NCT06318169Phase 3Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Role: lead

NCT06419374Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Role: lead