Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

30.8%

8 terminated/withdrawn out of 26 trials

Success Rate

68.0%

-18.6% vs industry average

Late-Stage Pipeline

15%

4 trials in Phase 3/4

Results Transparency

71%

12 of 17 completed trials have results

Key Signals

12 with results

Enrollment Performance

Analytics

Phase 1
18(69.2%)
Phase 3
4(15.4%)
Phase 2
4(15.4%)
26Total
Phase 1(18)
Phase 3(4)
Phase 2(4)

Activity Timeline

Global Presence

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Clinical Trials (26)

Showing 20 of 26 trials
NCT07073183Phase 1Withdrawn

Safety and Tolerability of CVHNLC Plus Pembrolizumab in Patients With Squamous Non Small-Cell Lung Cancer (sqNSCLC)

Role: lead

NCT05446740Phase 1Completed

A Study on the Safety, Reactogenicity and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Role: collaborator

NCT05938387Phase 1Completed

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

Role: lead

NCT05960097Phase 2Completed

A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults

Role: collaborator

NCT05823974Phase 1Completed

A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Role: collaborator

NCT03713086Phase 1Completed

A Study to Assess the Safety, Reactogenicity and Immune Response of CureVac's Candidate Rabies mRNA Vaccine in Healthy Adults

Role: lead

NCT05260437Phase 1Completed

Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants

Role: collaborator

NCT04652102Phase 2Completed

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

Role: lead

NCT04674189Phase 3Completed

A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19

Role: lead

NCT04515147Phase 2Completed

A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19

Role: lead

NCT05252338Phase 1Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVSQIV in Healthy Adults

Role: lead

NCT04449276Phase 1Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19

Role: lead

NCT03164772Phase 1Completed

Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC

Role: collaborator

NCT04860258Phase 3Terminated

COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV in Adults With Co-morbidities

Role: lead

NCT03291002Phase 1Unknown

Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC

Role: lead

NCT04838847Phase 3Withdrawn

A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19

Role: lead

NCT04848467Phase 3Withdrawn

COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older

Role: collaborator

NCT03203005Phase 1Completed

IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients

Role: collaborator

NCT02241135Phase 1Completed

RNActive® Rabies Vaccine (CV7201) in Healthy Adults

Role: lead

NCT02238756Phase 1Completed

Safety and Tolerability of CV8102 Alone and in Combination With a Rabies Virus Vaccine in Healthy Adults

Role: lead