Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.7%

2 terminated/withdrawn out of 23 trials

Success Rate

89.5%

+3.0% vs industry average

Late-Stage Pipeline

17%

4 trials in Phase 3/4

Results Transparency

29%

5 of 17 completed trials have results

Key Signals

1 recruiting5 with results

Enrollment Performance

Analytics

Phase 2

7(35.0%)

N/A

6(30.0%)

Phase 3

2(10.0%)

Phase 4

2(10.0%)

Phase 1

2(10.0%)

Early Phase 1

1(5.0%)

20Total

Phase 2(7)

N/A(6)

Phase 3(2)

Phase 4(2)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials

NCT04341779Not ApplicableActive Not Recruiting

Simplifying Treatment and Monitoring for HIV (STREAM HIV)

Role: collaborator

NCT04734652Phase 2Completed

INSTI's For The Management of HIV-associated TB

Role: lead

NCT06087913Phase 1Completed

Safety and PK Multi-dose Study of TAF/EVG Vaginal Insert

Role: collaborator

NCT05175794Completed

Triage Test for All Oral DR-TB Regimen (TRiAD Study)

Role: lead

NCT05633056Not ApplicableRecruiting

An Adaptive Randomized Controlled Trial

Role: collaborator

NCT06135974Early Phase 1Completed

Vaginal lIve Biotherapeutic RANdomized Trial

Role: collaborator

NCT04746547Phase 4Unknown

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB

Role: collaborator

NCT03237182Phase 4Terminated

The Individualized M(X) Drug-resistant TB Treatment Strategy Study

Role: lead

NCT04032730Not ApplicableCompleted

Promoting Engagement in the Drug Resistant TB-HIV Care Continuum in South Africa PRAXIS Study

Role: lead

NCT03227731Phase 2Completed

Immediate or Deferred Pre-exposure Prophylaxis for HIV Prevention: Safe Options for Pregnant and Lactating Women

Role: collaborator

NCT03162107Completed

Promoting Engagement in the Drug Resistant TB/HIV Care Continuum in South Africa

Role: lead

NCT02654613Not ApplicableCompleted

Scaling up TB and HIV Treatment Integration

Role: lead

NCT01691768Phase 2Completed

Implementation Effectiveness and Safety of Tenofovir Gel Provision Through Family Planning Services

Role: lead

NCT02114684Phase 1Completed

Improving Retreatment Success (IMPRESS)

Role: lead

NCT02735590Phase 2Unknown

The Correlate of Risk Targeted Intervention Study

Role: collaborator

NCT03407586Not ApplicableCompleted

STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women

Role: lead

NCT01387022Not ApplicableCompleted

Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression

Role: lead

NCT01539005Completed

Tuberculosis Recurrence Upon Treatment With Highly Active Antiretroviral Therapy

Role: lead

NCT01187979Phase 2Completed

Reducing HIV in Adolescents

Role: lead

NCT00408642Phase 3Completed

An Enhanced Adherence Support Programme for Highly Active Antiretroviral Therapy (HAART)

Role: lead