Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

10.3%

4 terminated/withdrawn out of 39 trials

Success Rate

81.0%

-5.5% vs industry average

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

24%

4 of 17 completed trials have results

Key Signals

9 recruiting4 with results

Enrollment Performance

Analytics

Phase 2
14(66.7%)
N/A
4(19.0%)
Phase 3
2(9.5%)
Phase 1
1(4.8%)
21Total
Phase 2(14)
N/A(4)
Phase 3(2)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (39)

Showing 20 of 39 trials
NCT07563010Phase 2Not Yet Recruiting

Menin-Inhibitor Targeted Maintenance in AML

Role: lead

NCT01351545Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Role: lead

NCT04904588Phase 2Active Not Recruiting

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Role: lead

NCT06859424Phase 2Recruiting

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Role: lead

NCT03619551Phase 2Active Not Recruiting

Conditioning SCID Infants Diagnosed Early

Role: lead

NCT05600426Phase 3Active Not Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

Role: collaborator

NCT06001385Phase 2Active Not Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Role: lead

NCT05784415Completed

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

Role: collaborator

NCT05224661Active Not Recruiting

Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events

Role: lead

NCT03904134Not ApplicableCompleted

Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702)

Role: lead

NCT01166009Recruiting

CIBMTR Research Database

Role: lead

NCT02793544Phase 2Completed

HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide

Role: lead

NCT03971799Phase 1Active Not Recruiting

Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia

Role: lead

NCT06224413Recruiting

A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel

Role: collaborator

NCT02450708Not ApplicableActive Not Recruiting

Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes

Role: collaborator

NCT00785525Phase 3Recruiting

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

Role: lead

NCT03718546Completed

Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors

Role: lead

NCT06271512Recruiting

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

Role: collaborator

NCT03992352Completed

Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704)

Role: lead

NCT01696461Phase 2Completed

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Role: lead