Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

17.4%

4 terminated/withdrawn out of 23 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

94%

15 of 16 completed trials have results

Key Signals

2 recruiting15 with results

Enrollment Performance

Analytics

Phase 1
17(73.9%)
Phase 2
6(26.1%)
23Total
Phase 1(17)
Phase 2(6)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT07430202Phase 1Not Yet Recruiting

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Role: collaborator

NCT04093167Phase 2Recruiting

Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

Role: collaborator

NCT04918186Phase 2Recruiting

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Role: collaborator

NCT04787991Phase 1Completed

Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Role: collaborator

NCT01239134Phase 1Completed

Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors

Role: collaborator

NCT03835533Phase 1Completed

Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations

Role: collaborator

NCT04426201Phase 2Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )

Role: collaborator

NCT03461952Phase 2Terminated

Nivolumab Ipilimumab in Patients With hyperMutated Cancers Detected in Blood (NIMBLe)

Role: collaborator

NCT03651271Phase 2Completed

Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancer

Role: collaborator

NCT02425306Phase 1Terminated

Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma

Role: collaborator

NCT03214250Phase 1Completed

Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Role: collaborator

NCT02963831Phase 1Completed

A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies

Role: collaborator

NCT02643303Phase 1Completed

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Role: collaborator

NCT02716805Phase 1Terminated

Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant

Role: collaborator

NCT01975831Phase 1Completed

A Phase 1 Study to Evaluate MEDI4736 in Combination With Tremelimumab

Role: collaborator

NCT02336165Phase 2Completed

Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastoma

Role: collaborator

NCT02431559Phase 1Completed

Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer

Role: collaborator

NCT02898116Phase 1Completed

Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer

Role: collaborator

NCT03164772Phase 1Completed

Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC

Role: collaborator

NCT00142454Phase 1Completed

NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting)

Role: collaborator