Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

3.1%

1 terminated/withdrawn out of 32 trials

Success Rate

96.2%

+9.6% vs industry average

Late-Stage Pipeline

38%

12 trials in Phase 3/4

Results Transparency

52%

13 of 25 completed trials have results

Key Signals

5 recruiting13 with results

Enrollment Performance

Analytics

Phase 1
10(31.3%)
Phase 2
10(31.3%)
Phase 3
9(28.1%)
Phase 4
3(9.4%)
32Total
Phase 1(10)
Phase 2(10)
Phase 3(9)
Phase 4(3)

Activity Timeline

Global Presence

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Clinical Trials (32)

Showing 20 of 32 trials
NCT06810167Phase 3Recruiting

Assessing Tenapanor as a Treatment of CF-related Constipation.

Role: collaborator

NCT07382167Phase 3Recruiting

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Role: lead

NCT05995899Phase 4Completed

Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation

Role: collaborator

NCT05643534Phase 3Recruiting

Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years

Role: lead

NCT06553547Phase 2Recruiting

4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs

Role: lead

NCT05905926Phase 3Enrolling By Invitation

Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C

Role: lead

NCT06460038Phase 2Recruiting

Tenapanor in Synucleinopathy-Related Constipation

Role: collaborator

NCT06203444Phase 1Completed

An Open-label Study to Evaluate the Pharmacokinetics of Oral Tenapanor in Breast Milk of Lactating Females

Role: lead

NCT03427125Phase 3Completed

A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis

Role: lead

NCT04549597Phase 4Completed

Study to Evaluate the Use of Tenapanor as Core Therapy in the Treatment of Hyperphosphatemia

Role: lead

NCT03988920Phase 4Completed

A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HP

Role: lead

NCT03824587Phase 2Completed

Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy

Role: lead

NCT04780841Phase 2Completed

A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia

Role: lead

NCT02081534Phase 2Completed

Dose Finding Study to Treat High Phosphate Levels in the Blood.

Role: lead

NCT02727751Phase 3Completed

A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C

Role: lead

NCT02675998Phase 3Completed

An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)

Role: lead

NCT01764854Phase 2Completed

Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis

Role: lead

NCT01847092Phase 2Completed

A Study in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria

Role: lead

NCT02686138Phase 3Completed

A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C

Role: lead

NCT02621892Phase 3Completed

A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C

Role: lead