Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

5.3%

3 terminated/withdrawn out of 57 trials

Success Rate

88.9%

+2.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

29%

7 of 24 completed trials have results

Key Signals

7 recruiting7 with results

Enrollment Performance

Analytics

N/A
24(68.6%)
Phase 1
6(17.1%)
Phase 2
4(11.4%)
Early Phase 1
1(2.9%)
35Total
N/A(24)
Phase 1(6)
Phase 2(4)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (57)

Showing 20 of 57 trials
NCT05989035Not ApplicableCompleted

Effects of MetAP2 Inhibition on Bioenergetics and Aging-associated Characteristics in Adipose Tissue in Healthy Participants

Role: lead

NCT06908057Active Not Recruiting

Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)

Role: lead

NCT02274805Completed

Collection of Human Tissue Samples From the Neck Region for Characterization of Its Molecular and Biochemical Signatures

Role: lead

NCT06993454Not ApplicableRecruiting

Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis

Role: lead

NCT01827527Completed

Magnetic Resonance & Optical Spectroscopy Validation

Role: lead

NCT07516509Not Yet Recruiting

Determining Cell- and Spatially-distinct Skeletal Muscle Transcriptional Aberrations in Insulin Resistance

Role: lead

NCT05820490Completed

ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks

Role: lead

NCT05379348Completed

Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease

Role: lead

NCT03971955Active Not Recruiting

CharacterIzation of Adult Onset Autoimmune Diabetes

Role: lead

NCT02663362Recruiting

Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications

Role: lead

NCT04334343Not ApplicableActive Not Recruiting

Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)

Role: lead

NCT02817659Phase 1Active Not Recruiting

To Determine Tolerability to Glucagon Infusion in Obese Subjects

Role: lead

NCT01911091Not ApplicableActive Not Recruiting

Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)

Role: lead

NCT04805970Active Not Recruiting

REsearching Covid-19 Outcomes in Diabetes (RECODE)

Role: lead

NCT04164966Active Not Recruiting

Development of Novel Biomarkers for the Early Diagnosis of Type 1 Diabetes

Role: lead

NCT04754581Not ApplicableActive Not Recruiting

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes

Role: lead

NCT03139305Phase 1Active Not Recruiting

Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects

Role: lead

NCT05662865Phase 1Active Not Recruiting

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers

Role: lead

NCT01911104Not ApplicableActive Not Recruiting

Exercise Resistance in Type 2 Diabetes

Role: lead

NCT06602141Not ApplicableRecruiting

Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise

Role: lead