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Publications

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Trial Results

0

Published trial results

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Total citations

Drug Portfolio

Analytics

Trial Phases

Phase 11
Phase 29
Phase 310
Phase 41

Trial Status

Completed15
Recruiting1
Other3

Role Distribution

Other Roles19

Activity Timeline

Clinical Trials (19)

NCT07156578Phase 2Enrolling By Invitation
A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)
Hypothalamic Obesity
StudychairStart date: 2025-11-10
NCT06760546Phase 3Recruiting
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Childhood-onset Combined Pituitary Hormone DeficiencyHypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic Form+3 more
StudychairStart date: 2025-09-23
NCT06772597Phase 2Active Not Recruiting
A Study of Setmelanotide in Patients With Prader-Willi Syndrome
HyperphagiaObesityPrader-Willi Syndrome
StudychairStart date: 2025-03-04
NCT06596135Phase 3Completed
Open-Label Extension Study of Setmelanotide
Obesity Associated With Defects in Leptin-melanocortin Pathway
StudychairStart date: 2024-10-21
NCT06046443Phase 2Completed
A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity
Hypothalamic Obesity
StudychairStart date: 2024-07-11
NCT05774756Phase 3Active Not Recruiting
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
Hypothalamic Obesity
StudychairStart date: 2023-04-26
NCT04966741Phase 3Completed
Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity
Bardet-Biedl SyndromeLEPR Deficiency ObesityPCSK1 Deficiency Obesity+1 more
StudychairStart date: 2022-03-08
NCT05093634Phase 3Completed
EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway
Genetic ObesityObesity
StudychairStart date: 2021-12-10

Showing 10 of 19 trials

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Collaboration Network

1 collaborators·0 connections
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CO
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CO
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Clinical Trials (19)

Showing 19 of 19 trials

NCT07156578Phase 2StudyChair

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

Hypothalamic Obesity
Enrolling By Invitation
NCT06760546Phase 3StudyChair

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Childhood-onset Combined Pituitary Hormone DeficiencyHypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic Form+3 more
Recruiting
NCT06772597Phase 2StudyChair

A Study of Setmelanotide in Patients With Prader-Willi Syndrome

HyperphagiaObesityPrader-Willi Syndrome
Active Not Recruiting
NCT06596135Phase 3StudyChair

Open-Label Extension Study of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway
Completed
NCT06046443Phase 2StudyChair

A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity

Hypothalamic Obesity
Completed
NCT05774756Phase 3StudyChair

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic Obesity
Active Not Recruiting
NCT04966741Phase 3StudyChair

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

Bardet-Biedl SyndromeLEPR Deficiency ObesityPCSK1 Deficiency Obesity+1 more
Completed
NCT05194124Phase 3StudyChair

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl SyndromePOMC Deficiency
Completed
NCT05093634Phase 3StudyChair

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Genetic ObesityObesity
Completed
NCT04963231Phase 2StudyChair

DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway

Genetic Obesity
Completed
NCT05046132Phase 4StudyChair

Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

Healthy
Completed
NCT04725240Phase 2StudyChair

Open-Label Study of Setmelanotide in Hypothalamic Obesity

Hypothalamic Obesity
Completed
NCT03746522Phase 3StudyChair

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Alström Syndrome (AS)Bardet Biedl Syndrome (BBS)
Completed
NCT03651765Phase 2/3StudyChair

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway
Completed
NCT03287960Phase 3StudyChair

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity
Completed
NCT02896192Phase 3StudyChair

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity
Completed
NCT03013543Phase 2StudyChair

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Genetic ObesityObesityObesity Due to Melanocortin 4 Receptor Deficiency
Completed
NCT02041195Phase 1/2StudyChair

Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

Overweight and Obesity
Completed
NCT01749137Phase 2StudyChair

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

Overweight
Completed

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