Setmelanotide
Setmelanotide is a pharmaceutical drug with 21 clinical trials. Currently 5 active trials ongoing. Historical success rate of 100.0%.
Success Metrics
Based on 15 completed trials
Phase Distribution
Phase Distribution
2
Early Stage
9
Mid Stage
10
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
100.0%
15 of 15 finished
0.0%
0 ended early
5
trials recruiting
21
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a)
Open-Label Extension Study of Setmelanotide
Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Clinical Trials (21)
Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a)
Open-Label Extension Study of Setmelanotide
Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
A Study of Setmelanotide in Patients With Prader-Willi Syndrome
EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway
DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway
Long Term Extension Trial of Setmelanotide
Open-Label Study of Setmelanotide in Hypothalamic Obesity
Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity
Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants
Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity
Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity
Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity
Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants
Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients
Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome
Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity
Setmelanotide in a Single Patient With Partial Lipodystrophy
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 21