Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
8(57%)
Results Posted
167%(5 trials)
Terminated
2(14%)

Phase Distribution

Ph early_phase_1
1
7%
Ph phase_2
2
14%
Ph not_applicable
1
7%
Ph phase_1
5
36%
Ph phase_3
4
29%

Phase Distribution

6

Early Stage

2

Mid Stage

4

Late Stage

Phase Distribution13 total trials
Early Phase 1First-in-human
1(7.7%)
Phase 1Safety & dosage
5(38.5%)
Phase 2Efficacy & side effects
2(15.4%)
Phase 3Large-scale testing
4(30.8%)
N/ANon-phased studies
1(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

60.0%

3 of 5 finished

Non-Completion Rate

40.0%

2 ended early

Currently Active

8

trials recruiting

Total Trials

14

all time

Status Distribution
Active(8)
Completed(3)
Terminated(2)
Other(1)

Detailed Status

Active, not recruiting5
Completed3
Recruiting3
Terminated2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
8
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (7.7%)
Phase 15 (38.5%)
Phase 22 (15.4%)
Phase 34 (30.8%)
N/A1 (7.7%)

Trials by Status

completed321%
recruiting321%
active_not_recruiting536%
terminated214%
unknown17%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT04804644Phase 3

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
NCT02993146Phase 1

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT02589522Phase 1

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

Active Not Recruiting
NCT02015117Phase 1

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT01592968Phase 3

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

Active Not Recruiting
NCT07443397Phase 3

Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients.

Recruiting
NCT02696993Phase 1

Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer

Active Not Recruiting
NCT06328686Early Phase 1

Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases

Recruiting
NCT04588246Phase 3

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Terminated
NCT01217411Phase 1

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Terminated
NCT01622868Phase 2

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Completed
NCT05737589

Circulating Tumor DNA and T Cell Repertoire Predict Radiotherapeutic Outcomes in NSCLC Patients With Brain Metastasis

Unknown
NCT02220491Not Applicable

Whole Brain Radiotherapy Versus Volumetric Modulated Arc Therapy for Brain Metastases

Completed
NCT04338867Phase 2

Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients

Completed

All 14 trials loaded

Drug Details

Intervention Type
RADIATION
Total Trials
14