Success Metrics

Clinical Success Rate
85.2%

Based on 127 completed trials

Completion Rate
85%(127/149)
Active Trials
7(4%)
Results Posted
39%(50 trials)
Terminated
22(12%)

Phase Distribution

Ph not_applicable
16
9%
Ph early_phase_1
1
1%
Ph phase_4
38
21%
Ph phase_1
16
9%
Ph phase_2
47
26%
Ph phase_3
51
28%

Phase Distribution

17

Early Stage

47

Mid Stage

89

Late Stage

Phase Distribution169 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
16(9.5%)
Phase 2Efficacy & side effects
47(27.8%)
Phase 3Large-scale testing
51(30.2%)
Phase 4Post-market surveillance
38(22.5%)
N/ANon-phased studies
16(9.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.9%

127 of 157 finished

Non-Completion Rate

19.1%

30 ended early

Currently Active

7

trials recruiting

Total Trials

179

all time

Status Distribution
Active(9)
Completed(127)
Terminated(30)
Other(13)

Detailed Status

Completed127
Terminated22
unknown12
Withdrawn8
Recruiting4
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
179
Active
7
Success Rate
85.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 116 (9.5%)
Phase 247 (27.8%)
Phase 351 (30.2%)
Phase 438 (22.5%)
N/A16 (9.5%)

Trials by Status

terminated2212%
active_not_recruiting32%
withdrawn84%
not_yet_recruiting21%
suspended11%
unknown127%
completed12771%
recruiting42%

Recent Activity

Clinical Trials (179)

Showing 20 of 179 trialsScroll for more
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
NCT01351753Phase 2

Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity

Terminated
NCT05975580Phase 4

Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

Recruiting
NCT02273804Phase 3

Topiramate and Severe Obesity

Completed
NCT03196466

Population Pharmacokinetics of Antiepileptic in Pediatrics

Completed
NCT06799169Phase 4

Management of Acute Tinnitus With Migraine Medications

Active Not Recruiting
NCT05756764

Anti-obesity Pharmacotherapy and Inflammation

Active Not Recruiting
NCT04572217Phase 2

Medications After Adolescent Bariatric Surgery

Withdrawn
NCT05748483Phase 3

Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine

Active Not Recruiting
NCT02201251Phase 3

A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy

Completed
NCT00394095Phase 4

Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine

Completed
NCT03667846Phase 2

Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD

Recruiting
NCT01689649Phase 4

A Study to Assess Tolerability and Efficacy of Topiramate Monotherapy in Recently Diagnosed Patients With Epilepsy

Completed
NCT01950520Phase 2

Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

Completed
NCT06499116Phase 4

Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care

Not Yet Recruiting
NCT01765218Phase 1

Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy

Terminated
NCT06282783Phase 1

Studying Topiramate for Re-Activating the HIV-1 Reservoir

Not Yet Recruiting
NCT05403229Phase 2

The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing Loss

Recruiting
NCT03176953Phase 2

Topiramate and Prolonged Exposure

Completed
NCT02878798Phase 2

Topiramate for Cryptogenic Sensory Peripheral Neuropathy in Metabolic Syndrome (CSPN)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
179