Success Metrics

Clinical Success Rate
86.2%

Based on 25 completed trials

Completion Rate
86%(25/29)
Active Trials
9(21%)
Results Posted
76%(19 trials)
Terminated
4(10%)

Phase Distribution

Ph phase_3
20
48%
Ph phase_4
3
7%
Ph phase_2
10
24%
Ph phase_1
2
5%

Phase Distribution

2

Early Stage

10

Mid Stage

23

Late Stage

Phase Distribution35 total trials
Phase 1Safety & dosage
2(5.7%)
Phase 2Efficacy & side effects
10(28.6%)
Phase 3Large-scale testing
20(57.1%)
Phase 4Post-market surveillance
3(8.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

25 of 30 finished

Non-Completion Rate

16.7%

5 ended early

Currently Active

9

trials recruiting

Total Trials

42

all time

Status Distribution
Active(10)
Completed(25)
Terminated(5)
Other(2)

Detailed Status

Completed25
Active, not recruiting5
Recruiting4
Terminated4
unknown2
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
42
Active
9
Success Rate
86.2%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (5.7%)
Phase 210 (28.6%)
Phase 320 (57.1%)
Phase 43 (8.6%)

Trials by Status

enrolling_by_invitation12%
recruiting410%
completed2560%
unknown25%
withdrawn12%
terminated410%
active_not_recruiting512%

Recent Activity

Clinical Trials (42)

Showing 20 of 42 trialsScroll for more
NCT05344469

A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosis

Recruiting
NCT06141473Phase 3

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting
NCT05156281Phase 3

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Active Not Recruiting
NCT04586023Phase 3

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Active Not Recruiting
NCT04799288Phase 1

Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis

Recruiting
NCT05147220Phase 3

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Active Not Recruiting
NCT04586010Phase 3

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Active Not Recruiting
NCT06372145Phase 3

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Active Not Recruiting
NCT04410965Phase 4

Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chinese RMS Patients Treated With Teriflunomide 14 mg Once Daily for 24 Weeks

Completed
NCT07065968Phase 2

The Efficacy and Safety of Combined Teriflunomide and High-dose Dexamethasone in Newly Diagnosed Primary Immune Thrombocytopenia (TEMPO-2)

Recruiting
NCT06176235Phase 2

Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia

Withdrawn
NCT04410978Phase 3

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 1)

Completed
NCT04338022Phase 3

Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

Terminated
NCT02425644Phase 3

Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis

Completed
NCT04338061Phase 3

Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

Terminated
NCT04056897Phase 2

Comparative Study of the Efficacy and Safety of BCD-132 With Teriflunomide and Placebo in Multiple Sclerosis

Completed
NCT02201108Phase 3

Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis

Completed
NCT06705608

Examining the Risk of Skin Cancer in Multiple Sclerosis Patients Using Fingolimod: a Population-Based Study

Completed
NCT05385744Phase 3

An International, Multicenter, Randomized, Double-Blind, Double-Masked Study of the Efficacy and Safety of BCD-132 (JSC BIOCAD, Russia) Using an Active Reference Drug (Teriflunomide) for the Treatment of Patients With Multiple Sclerosis

Completed
NCT06190145Phase 2

Teriflunomide for Steroid-resistant/Relapse Immune Thrombocytopenia

Unknown

Drug Details

Intervention Type
OTHER
Total Trials
42