Success Metrics

Clinical Success Rate
78.9%

Based on 333 completed trials

Completion Rate
79%(333/422)
Active Trials
156(22%)
Results Posted
61%(202 trials)
Terminated
89(13%)

Phase Distribution

Ph phase_1
269
39%
Ph not_applicable
12
2%
Ph early_phase_1
19
3%
Ph phase_2
323
46%
Ph phase_3
59
8%
Ph phase_4
4
1%

Phase Distribution

288

Early Stage

323

Mid Stage

63

Late Stage

Phase Distribution686 total trials
Early Phase 1First-in-human
19(2.8%)
Phase 1Safety & dosage
269(39.2%)
Phase 2Efficacy & side effects
323(47.1%)
Phase 3Large-scale testing
59(8.6%)
Phase 4Post-market surveillance
4(0.6%)
N/ANon-phased studies
12(1.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

333 of 444 finished

Non-Completion Rate

25.0%

111 ended early

Currently Active

156

trials recruiting

Total Trials

695

all time

Status Distribution
Active(171)
Completed(333)
Terminated(111)
Other(80)

Detailed Status

Completed333
Terminated89
Recruiting86
unknown79
Active, not recruiting70
Withdrawn22

Development Timeline

Analytics

Development Status

Total Trials
695
Active
156
Success Rate
78.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 119 (2.8%)
Phase 1269 (39.2%)
Phase 2323 (47.1%)
Phase 359 (8.6%)
Phase 44 (0.6%)
N/A12 (1.7%)

Trials by Status

completed33348%
recruiting8612%
active_not_recruiting7010%
not_yet_recruiting152%
suspended10%
terminated8913%
unknown7911%
withdrawn223%

Recent Activity

Clinical Trials (695)

Showing 20 of 695 trialsScroll for more
NCT07569042Phase 1

A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma

Recruiting
NCT06995872Phase 1

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

Recruiting
NCT05095376Phase 3

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Active Not Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT05432804Phase 1

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Recruiting
NCT05629702Phase 2

ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids

Recruiting
NCT07452458Phase 3

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Not Yet Recruiting
NCT03581292Phase 2

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

Active Not Recruiting
NCT03491683Phase 1

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

Active Not Recruiting
NCT03970447Phase 2

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Recruiting
NCT06556563Phase 3

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Recruiting
NCT04200443Phase 2

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

Active Not Recruiting
NCT02595424Phase 2

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Active Not Recruiting
NCT06410248Phase 1

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recruiting
NCT07195591Phase 3

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

Recruiting
NCT06625047Phase 4

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Completed
NCT06012695Phase 1

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Recruiting
NCT01638546Phase 2

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

Active Not Recruiting
NCT07297212Phase 2

A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma

Recruiting
NCT02152982Phase 2

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
695