Success Metrics

Clinical Success Rate
80.0%

Based on 20 completed trials

Completion Rate
80%(20/25)
Active Trials
6(15%)
Results Posted
60%(12 trials)
Terminated
5(13%)

Phase Distribution

Ph phase_2
14
35%
Ph phase_3
9
23%
Ph phase_1
16
40%

Phase Distribution

16

Early Stage

14

Mid Stage

9

Late Stage

Phase Distribution39 total trials
Phase 1Safety & dosage
16(41.0%)
Phase 2Efficacy & side effects
14(35.9%)
Phase 3Large-scale testing
9(23.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

76.9%

20 of 26 finished

Non-Completion Rate

23.1%

6 ended early

Currently Active

6

trials recruiting

Total Trials

40

all time

Status Distribution
Active(8)
Completed(20)
Terminated(6)
Other(6)

Detailed Status

Completed20
Recruiting6
unknown6
Terminated5
Not yet recruiting2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
40
Active
6
Success Rate
80.0%
Most Advanced
Phase 3

Trials by Phase

Phase 116 (41.0%)
Phase 214 (35.9%)
Phase 39 (23.1%)

Trials by Status

completed2050%
recruiting615%
not_yet_recruiting25%
withdrawn13%
unknown615%
terminated513%

Recent Activity

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more
NCT06850090Phase 3

Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial

Recruiting
NCT04868773Phase 1

Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy

Completed
NCT04920032Phase 1

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

Recruiting
NCT05854498Phase 2

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

Recruiting
NCT03223779Phase 1

Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer

Completed
NCT06346392Phase 3

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Recruiting
NCT05343013Phase 2

TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Recruiting
NCT05600309Phase 3

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)-China Extension Study

Completed
NCT07196345Phase 1

TAS-102 Plus Radiotherapy in Elderly ESCC

Not Yet Recruiting
NCT05064059Phase 3

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)

Completed
NCT05328908Phase 3

A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

Terminated
NCT07116577Phase 2

Radiotherapy Combined QL1706, TAS-102 and Bevacizumab in mCRC

Not Yet Recruiting
NCT05481463Phase 2

Surufatinib Combined With TAS-102 in Third-line and Later-line Therapy of Patients With Advanced Pancreatic Cancer

Completed
NCT02261532Phase 1

A Phase I Study of TAS-102 in Solid Tumors

Completed
NCT04999761Phase 1

AB122 Platform Study

Recruiting
NCT01607957Phase 3

Study of TAS-102 in Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies

Completed
NCT01867879Phase 1

Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors

Completed
NCT01916447Phase 1

A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.

Completed
NCT01867866Phase 1

Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone

Completed
NCT02301117Phase 1

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Completed

Drug Details

Intervention Type
COMBINATION PRODUCT
Total Trials
40