Success Metrics

Clinical Success Rate
90.0%

Based on 224 completed trials

Completion Rate
90%(224/249)
Active Trials
8(3%)
Results Posted
64%(144 trials)
Terminated
25(8%)

Phase Distribution

Ph not_applicable
25
8%
Ph phase_4
94
32%
Ph early_phase_1
2
1%
Ph phase_2
45
15%
Ph phase_3
84
28%
Ph phase_1
27
9%

Phase Distribution

29

Early Stage

45

Mid Stage

178

Late Stage

Phase Distribution277 total trials
Early Phase 1First-in-human
2(0.7%)
Phase 1Safety & dosage
27(9.7%)
Phase 2Efficacy & side effects
45(16.2%)
Phase 3Large-scale testing
84(30.3%)
Phase 4Post-market surveillance
94(33.9%)
N/ANon-phased studies
25(9.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.8%

224 of 258 finished

Non-Completion Rate

13.2%

34 ended early

Currently Active

8

trials recruiting

Total Trials

295

all time

Status Distribution
Active(10)
Completed(224)
Terminated(34)
Other(27)

Detailed Status

Completed224
unknown27
Terminated25
Withdrawn9
Recruiting7
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
295
Active
8
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.7%)
Phase 127 (9.7%)
Phase 245 (16.2%)
Phase 384 (30.3%)
Phase 494 (33.9%)
N/A25 (9.0%)

Trials by Status

recruiting72%
completed22476%
active_not_recruiting10%
terminated258%
not_yet_recruiting21%
withdrawn93%
unknown279%

Recent Activity

Clinical Trials (295)

Showing 20 of 295 trialsScroll for more
NCT02363335Phase 1

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Completed
NCT07390110

Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)

Completed
NCT01035879Phase 2

Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of MBX-2982 Administered Daily for 4 Weeks as Monotherapy in Patients With Type 2 Diabetes

Completed
NCT07804381Phase 2

Disease-modifying Efficacy of Sitagliptin Therapy in Early-stage Parkinson's Disease

Not Yet Recruiting
NCT06851962Phase 4

Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.

Completed
NCT07567781Phase 1

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.

Completed
NCT07003542Phase 2

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

Recruiting
NCT07634380Phase 1

Sitagliptin With Pembro in RCC and Melanoma

Recruiting
NCT07717242Phase 2

Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder Cancer

Recruiting
NCT07711171Phase 4

Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild Cognitive Impairment

Recruiting
NCT07417631

Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.

Completed
NCT07599345

Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data

Completed
NCT07417618

INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)

Completed
NCT07599293

Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data

Completed
NCT07541781Phase 1

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

Recruiting
NCT06246799Phase 3

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Recruiting
NCT06263673Phase 4

Anti-Diabetic Medications to Fight PD and LBD

Completed
NCT07096063

Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk

Completed
NCT02650427Phase 1

A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver Resection

Completed
NCT03738878Phase 4

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

Terminated

Drug Details

Intervention Type
OTHER
Total Trials
295