Success Metrics

Clinical Success Rate

72.2%

Based on 13 completed trials

Completion Rate

72%(13/18)

Active Trials

0(0%)

Results Posted

69%(9 trials)

Terminated

5(15%)

Phase Distribution

Ph phase_3

24%

Ph early_phase_1

Ph not_applicable

26%

Ph phase_2

29%

Ph phase_1

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution33 total trials

Early Phase 1First-in-human

3(9.1%)

Phase 1Safety & dosage

3(9.1%)

Phase 2Efficacy & side effects

10(30.3%)

Phase 3Large-scale testing

8(24.2%)

N/ANon-phased studies

9(27.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.9%

13 of 21 finished

Non-Completion Rate

38.1%

8 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(1)

Completed(13)

Terminated(8)

Other(12)

Detailed Status

Completed13

unknown12

Terminated5

Withdrawn3

Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

72.2%

Most Advanced

Phase 3

Trials by Phase

Early Phase 13 (9.1%)

Phase 13 (9.1%)

Phase 210 (30.3%)

Phase 38 (24.2%)

N/A9 (27.3%)

Trials by Status

withdrawn39%

terminated515%

unknown1235%

not_yet_recruiting13%

completed1338%

Recent Activity

0 active trials

Showing 5 of 34

completedearly_phase_1

Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes

NCT05907850

completednot_applicable

Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults

NCT05803811

unknownnot_applicable

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more

NCT05907850Early Phase 1

Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes

Completed

NCT05803811Not Applicable

Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults

Completed

NCT05881187Not Applicable

Pack Cross Linking for Infectious Keratitis

Unknown

NCT02863809Phase 1

Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

Completed

NCT01112072Phase 3

Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia

Unknown

NCT01464268Phase 3

Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia

Unknown

NCT04905108Phase 3

Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal Ectasia

Unknown

NCT04897503Phase 3

Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose

Unknown

NCT02622386Phase 2

The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis

Completed

NCT01190306Phase 3

Safety Study of the VEGA UV-A System to Treat Keratoconus

Terminated

NCT01398852Phase 3

Safety and Effectiveness Study of the VEGA UV-A System for Cross-linking in Eyes With Keratoconus and Ectasia

Terminated

NCT01398839Phase 3

Safety Study of the VEGA UV-A System to Treat Ectasia

Terminated

NCT04232800Phase 2

Riboflavin for Glutamate Reduction in Alcohol Withdrawal

Unknown

NCT04278378Not Applicable

Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Blood Pressure.

Completed

NCT04731727Early Phase 1

Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL)

Not Yet Recruiting

NCT03187912Phase 3

Accelerated Corneal Cross-linking With Different Riboflavin Solutions

Completed

NCT03432572Early Phase 1

Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets

Completed

NCT03151096Not Applicable

Pilot Evaluation of the Effect of Riboflavin Supplementation on Blood Pressure and Possible Effect Modification by the MTHFR C677T Genotype

Terminated

NCT01582880Phase 1

Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis

Completed

NCT02344238Not Applicable

Smart Capsule for Automatic Adherence Monitoring

Completed

Drug Details

Intervention Type: DRUG
Total Trials: 34