Success Metrics

Clinical Success Rate
87.0%

Based on 60 completed trials

Completion Rate
87%(60/69)
Active Trials
40(32%)
Results Posted
88%(53 trials)
Terminated
9(7%)

Phase Distribution

Ph phase_2
69
55%
Ph phase_3
13
10%
Ph not_applicable
1
1%
Ph phase_1
40
32%

Phase Distribution

40

Early Stage

69

Mid Stage

13

Late Stage

Phase Distribution123 total trials
Phase 1Safety & dosage
40(32.5%)
Phase 2Efficacy & side effects
69(56.1%)
Phase 3Large-scale testing
13(10.6%)
N/ANon-phased studies
1(0.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

78.9%

60 of 76 finished

Non-Completion Rate

21.1%

16 ended early

Currently Active

40

trials recruiting

Total Trials

125

all time

Status Distribution
Active(42)
Completed(60)
Terminated(16)
Other(7)

Detailed Status

Completed60
Recruiting20
Active, not recruiting20
Terminated9
unknown7
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
125
Active
40
Success Rate
87.0%
Most Advanced
Phase 3

Trials by Phase

Phase 140 (32.5%)
Phase 269 (56.1%)
Phase 313 (10.6%)
N/A1 (0.8%)

Trials by Status

completed6048%
not_yet_recruiting22%
recruiting2016%
active_not_recruiting2016%
terminated97%
unknown76%
withdrawn76%

Recent Activity

Clinical Trials (125)

Showing 20 of 125 trialsScroll for more
NCT06448754Phase 2

Volrustomig Priming Regimens Exploratory Phase II Platform Study

Recruiting
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT04332367Phase 2

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

Recruiting
NCT06043427Phase 2

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

Recruiting
NCT05642572Phase 2

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Recruiting
NCT05062980Phase 1

Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer

Terminated
NCT04310007Phase 2

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Active Not Recruiting
NCT04704934Phase 3

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Active Not Recruiting
NCT07098338Phase 2

A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06203600Phase 2

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Recruiting
NCT03527108Phase 2

Nivolumab Plus Ramucirumab in Patients With Recurrent, Advanced, Metastatic NSCLC

Active Not Recruiting
NCT07546812Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

Recruiting
NCT07594548Phase 1

Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Not Yet Recruiting
NCT05096663Phase 2

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Active Not Recruiting
NCT03650764Phase 1

Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Completed
NCT06251973Phase 2

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

Active Not Recruiting
NCT06445972Phase 1

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Recruiting
NCT04145349Phase 1

CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor

Completed
NCT06031688Phase 2

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Recruiting
NCT06616584Phase 2

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
125