Success Metrics

Clinical Success Rate
90.0%

Based on 9 completed trials

Completion Rate
90%(9/10)
Active Trials
0(0%)
Results Posted
44%(4 trials)
Terminated
1(9%)

Phase Distribution

Ph phase_2
5
45%
Ph phase_1
6
55%

Phase Distribution

6

Early Stage

5

Mid Stage

0

Late Stage

Phase Distribution11 total trials
Phase 1Safety & dosage
6(54.5%)
Phase 2Efficacy & side effects
5(45.5%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

90.0%

9 of 10 finished

Non-Completion Rate

10.0%

1 ended early

Currently Active

0

trials recruiting

Total Trials

11

all time

Status Distribution
Completed(9)
Terminated(1)
Other(1)

Detailed Status

Completed9
Terminated1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
11
Active
0
Success Rate
90.0%
Most Advanced
Phase 2

Trials by Phase

Phase 16 (54.5%)
Phase 25 (45.5%)

Trials by Status

terminated19%
unknown19%
completed982%

Recent Activity

Clinical Trials (11)

Showing 11 of 11 trials
NCT05064332Phase 1

A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)

Completed
NCT04092452Phase 2

A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa

Completed
NCT04413617Phase 2

TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE

Completed
NCT04575610Phase 2

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

Terminated
NCT04933799Phase 2

IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.

Unknown
NCT02996500Phase 2

Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate

Completed
NCT03308110Phase 1

Bioavailability and Food Effect Study of Two Formulations of PF-06650833

Completed
NCT02936154Phase 1

Study for MR Formulation of PF-06650833 in Healthy Adult Japanese Subjects

Completed
NCT02485769Phase 1

Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Oral Pf-06650833 In Healthy Subjects

Completed
NCT02609139Phase 1

Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects

Completed
NCT02224651Phase 1

Study to Evaluate Safety and Tolerability of Single Ascending Doses of Multiple Formulations of PF-06650833 in Healthy Subjects Under Fasted and Fed Conditions

Completed

All 11 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
11