Success Metrics

Clinical Success Rate
40.0%

Based on 4 completed trials

Completion Rate
40%(4/10)
Active Trials
0(0%)
Results Posted
250%(10 trials)
Terminated
6(60%)

Phase Distribution

Ph phase_2
2
20%
Ph phase_3
1
10%
Ph phase_1
7
70%

Phase Distribution

7

Early Stage

2

Mid Stage

1

Late Stage

Phase Distribution10 total trials
Phase 1Safety & dosage
7(70.0%)
Phase 2Efficacy & side effects
2(20.0%)
Phase 3Large-scale testing
1(10.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

40.0%

4 of 10 finished

Non-Completion Rate

60.0%

6 ended early

Currently Active

0

trials recruiting

Total Trials

10

all time

Status Distribution
Completed(4)
Terminated(6)

Detailed Status

Terminated6
Completed4

Development Timeline

Analytics

Development Status

Total Trials
10
Active
0
Success Rate
40.0%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (70.0%)
Phase 22 (20.0%)
Phase 31 (10.0%)

Trials by Status

terminated660%
completed440%

Recent Activity

0 active trials
Showing 5 of 10
completedphase_2

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

NCT03373383
terminatedphase_3

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

NCT03739840
terminatedphase_2

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

NCT03370120
terminatedphase_1

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

NCT04136444
completedphase_1

A Study to Test the Safety, and Tolerability of Padsevonil in Healthy Male Japanese Study Participants

NCT04075409
View all 10 trials

Clinical Trials (10)

Showing 10 of 10 trials
NCT03373383Phase 2

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

Completed
NCT03739840Phase 3

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Terminated
NCT03370120Phase 2

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Terminated
NCT04136444Phase 1

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Terminated
NCT04075409Phase 1

A Study to Test the Safety, and Tolerability of Padsevonil in Healthy Male Japanese Study Participants

Completed
NCT04013191Phase 1

A Study to Test the Safety and Tolerability of Single and Multiple Doses of Padsevonil in Adult and Elderly Study Participants

Completed
NCT04131517Phase 1

A Study to Test the Interaction of Padsevonil With Oral Contraceptives in Healthy Female Participants

Terminated
NCT04126343Phase 1

A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants

Terminated
NCT04039919Phase 1

A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol

Terminated
NCT03695094Phase 1

A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil

Completed

All 10 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
10