Success Metrics

Clinical Success Rate
100.0%

Based on 5 completed trials

Completion Rate
100%(5/5)
Active Trials
0(0%)
Results Posted
60%(3 trials)

Phase Distribution

Ph phase_3
3
43%
Ph phase_2
2
29%
Ph phase_1
2
29%

Phase Distribution

2

Early Stage

2

Mid Stage

3

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
2(28.6%)
Phase 2Efficacy & side effects
2(28.6%)
Phase 3Large-scale testing
3(42.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

71.4%

5 of 7 finished

Non-Completion Rate

28.6%

2 ended early

Currently Active

0

trials recruiting

Total Trials

7

all time

Status Distribution
Completed(5)
Terminated(2)

Detailed Status

Completed5
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
7
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 12 (28.6%)
Phase 22 (28.6%)
Phase 33 (42.9%)

Trials by Status

withdrawn229%
completed571%

Recent Activity

0 active trials
Showing 5 of 7
completedphase_3

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

NCT03759392
completedphase_3

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

NCT02929329
withdrawnphase_2

Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure Patients

NCT01077167
withdrawnphase_3

Omecamtiv Mecarbil Post-trial Access Study

NCT04464525
completedphase_2

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

NCT01300013
View all 7 trials

Clinical Trials (7)

Showing 7 of 7 trials
NCT03759392Phase 3

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

Completed
NCT02929329Phase 3

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

Completed
NCT01077167Phase 2

Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure Patients

Withdrawn
NCT04464525Phase 3

Omecamtiv Mecarbil Post-trial Access Study

Withdrawn
NCT01300013Phase 2

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Completed
NCT02601001Phase 1

Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese Adults

Completed
NCT01380223Phase 1

A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy Volunteers

Completed

All 7 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
7