Success Metrics

Clinical Success Rate
72.4%

Based on 181 completed trials

Completion Rate
72%(181/250)
Active Trials
146(30%)
Results Posted
81%(147 trials)
Terminated
69(14%)

Phase Distribution

Ph phase_3
75
15%
Ph early_phase_1
4
1%
Ph phase_2
207
42%
Ph phase_4
2
0%
Ph phase_1
193
39%
Ph not_applicable
5
1%

Phase Distribution

197

Early Stage

207

Mid Stage

77

Late Stage

Phase Distribution486 total trials
Early Phase 1First-in-human
4(0.8%)
Phase 1Safety & dosage
193(39.7%)
Phase 2Efficacy & side effects
207(42.6%)
Phase 3Large-scale testing
75(15.4%)
Phase 4Post-market surveillance
2(0.4%)
N/ANon-phased studies
5(1.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.8%

181 of 275 finished

Non-Completion Rate

34.2%

94 ended early

Currently Active

146

trials recruiting

Total Trials

489

all time

Status Distribution
Active(168)
Completed(181)
Terminated(94)
Other(46)

Detailed Status

Completed181
Recruiting90
Terminated69
Active, not recruiting56
unknown43
Withdrawn25

Development Timeline

Analytics

Development Status

Total Trials
489
Active
146
Success Rate
72.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.8%)
Phase 1193 (39.7%)
Phase 2207 (42.6%)
Phase 375 (15.4%)
Phase 42 (0.4%)
N/A5 (1.0%)

Trials by Status

not_yet_recruiting224%
withdrawn255%
active_not_recruiting5611%
recruiting9018%
completed18137%
terminated6914%
unknown439%
suspended31%

Recent Activity

Clinical Trials (489)

Showing 20 of 489 trialsScroll for more
NCT04115163Phase 2

Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer

Active Not Recruiting
NCT03424005Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Recruiting
NCT05422794Phase 1

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Recruiting
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT03606967Phase 2

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Recruiting
NCT07063745Phase 2

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Recruiting
NCT04892953Phase 2

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT06422143Phase 3

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Recruiting
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT07752394Phase 2

Penpulimab Combined With Chemotherapy for Patients With Locally Advanced Hypopharyngeal Carcinoma

Not Yet Recruiting
NCT06096844Phase 3

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Recruiting
NCT06439693Phase 2

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Recruiting
NCT07748611Phase 2

SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial

Not Yet Recruiting
NCT04999761Phase 1

AB122 Platform Study

Recruiting
NCT04310007Phase 2

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Active Not Recruiting
NCT07621718Phase 3

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Recruiting
NCT05285358Phase 1

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Recruiting
NCT07738341Phase 1

GB268 Monotherapy or Combination Therapy for Locally Advanced/Metastatic Breast Cancer (Phase Ib/Ⅱ)

Not Yet Recruiting
NCT05685602Phase 1

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

Suspended

Drug Details

Intervention Type
DRUG
Total Trials
489