Success Metrics

Clinical Success Rate
72.2%

Based on 182 completed trials

Completion Rate
72%(182/252)
Active Trials
149(30%)
Results Posted
81%(147 trials)
Terminated
70(14%)

Phase Distribution

Ph not_applicable
5
1%
Ph phase_1
194
39%
Ph phase_2
212
43%
Ph early_phase_1
4
1%
Ph phase_4
2
0%
Ph phase_3
78
16%

Phase Distribution

198

Early Stage

212

Mid Stage

80

Late Stage

Phase Distribution495 total trials
Early Phase 1First-in-human
4(0.8%)
Phase 1Safety & dosage
194(39.2%)
Phase 2Efficacy & side effects
212(42.8%)
Phase 3Large-scale testing
78(15.8%)
Phase 4Post-market surveillance
2(0.4%)
N/ANon-phased studies
5(1.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.7%

182 of 277 finished

Non-Completion Rate

34.3%

95 ended early

Currently Active

149

trials recruiting

Total Trials

498

all time

Status Distribution
Active(176)
Completed(182)
Terminated(95)
Other(45)

Detailed Status

Completed182
Recruiting90
Terminated70
Active, not recruiting59
unknown42
Not yet recruiting27

Development Timeline

Analytics

Development Status

Total Trials
498
Active
149
Success Rate
72.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.8%)
Phase 1194 (39.2%)
Phase 2212 (42.8%)
Phase 378 (15.8%)
Phase 42 (0.4%)
N/A5 (1.0%)

Trials by Status

suspended31%
not_yet_recruiting275%
terminated7014%
completed18237%
unknown428%
recruiting9018%
active_not_recruiting5912%
withdrawn255%

Recent Activity

Clinical Trials (498)

Showing 20 of 498 trialsScroll for more
NCT07226856Phase 2

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

Recruiting
NCT06393400Phase 1

CHemotherapy And Stool Transplant in PDAC (CHASe-PDAC)

Active Not Recruiting
NCT07491445Phase 3

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

Recruiting
NCT06996782Phase 1

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06096844Phase 3

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Recruiting
NCT07221474Phase 2

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

Recruiting
NCT07729956Phase 3

A Study of BL-B01D1 Plus an Anti-PD-1 Antibody Versus Nab-paclitaxel Plus an Anti-PD-1 Antibody in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Express PD-L1 (PANKU-Breast04)

Recruiting
NCT03257033Phase 3

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

Active Not Recruiting
NCT06423326Phase 2

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Recruiting
NCT05422794Phase 1

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Recruiting
NCT07845786Phase 2

Zanzalintinib and Pembrolizumab in First-Line Maintenance for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT04310007Phase 2

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Active Not Recruiting
NCT06608927Phase 3

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Active Not Recruiting
NCT03734029Phase 3

Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]

Completed
NCT07621718Phase 3

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT06103864Phase 3

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Recruiting
NCT07259317Phase 2

Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma

Recruiting
NCT06312176Phase 3

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
498