Success Metrics

Clinical Success Rate
65.9%

Based on 27 completed trials

Completion Rate
66%(27/41)
Active Trials
11(19%)
Results Posted
148%(40 trials)
Terminated
14(24%)

Phase Distribution

Ph phase_3
12
20%
Ph phase_4
4
7%
Ph phase_2
31
53%
Ph phase_1
10
17%
Ph not_applicable
2
3%

Phase Distribution

10

Early Stage

31

Mid Stage

16

Late Stage

Phase Distribution59 total trials
Phase 1Safety & dosage
10(16.9%)
Phase 2Efficacy & side effects
31(52.5%)
Phase 3Large-scale testing
12(20.3%)
Phase 4Post-market surveillance
4(6.8%)
N/ANon-phased studies
2(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.8%

27 of 43 finished

Non-Completion Rate

37.2%

16 ended early

Currently Active

11

trials recruiting

Total Trials

59

all time

Status Distribution
Active(12)
Completed(27)
Terminated(16)
Other(4)

Detailed Status

Completed27
Terminated14
Recruiting8
unknown4
Active, not recruiting3
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
59
Active
11
Success Rate
65.9%
Most Advanced
Phase 4

Trials by Phase

Phase 110 (16.9%)
Phase 231 (52.5%)
Phase 312 (20.3%)
Phase 44 (6.8%)
N/A2 (3.4%)

Trials by Status

active_not_recruiting35%
recruiting814%
completed2746%
not_yet_recruiting12%
withdrawn23%
terminated1424%
unknown47%

Recent Activity

Clinical Trials (59)

Showing 20 of 59 trialsScroll for more
NCT01861106Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

Recruiting
NCT04339777Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Recruiting
NCT05027945Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Recruiting
NCT06615050Phase 3

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Recruiting
NCT02918292Phase 2

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)

Completed
NCT07214688Phase 2

Fludarabine and Intermediate-dose TBI Followed by PTCy in Patients Undergoing Allo Transplant for Heme Malignancies

Recruiting
NCT03663335Phase 2

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients

Completed
NCT06365437Phase 2

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Terminated
NCT07340463Phase 2

The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment

Recruiting
NCT03842696Phase 1

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Active Not Recruiting
NCT03674411Phase 2

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Active Not Recruiting
NCT06799195Phase 2

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

Recruiting
NCT01780844Phase 2

A Study to Assess the Efficacy and Safety of ASKP1240 in de Novo Kidney Transplant Recipients

Completed
NCT03112603Phase 3

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Completed
NCT01350245Phase 2

Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor

Completed
NCT00429143Phase 1

A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative

Completed
NCT01532635Phase 2

A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives

Terminated
NCT04311632Phase 2

A Dose Escalation Study in de Novo Renal Transplantation

Completed
NCT04660539Phase 3

A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
59