Success Metrics

Clinical Success Rate
100.0%

Based on 16 completed trials

Completion Rate
100%(16/16)
Active Trials
4(19%)
Results Posted
50%(8 trials)

Phase Distribution

Ph not_applicable
2
10%
Ph phase_3
6
29%
Ph phase_4
2
10%
Ph phase_2
7
33%
Ph phase_1
2
10%

Phase Distribution

2

Early Stage

7

Mid Stage

8

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
2(10.5%)
Phase 2Efficacy & side effects
7(36.8%)
Phase 3Large-scale testing
6(31.6%)
Phase 4Post-market surveillance
2(10.5%)
N/ANon-phased studies
2(10.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

16 of 16 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

4

trials recruiting

Total Trials

21

all time

Status Distribution
Active(4)
Completed(16)
Other(1)

Detailed Status

Completed16
Active, not recruiting2
Recruiting2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
21
Active
4
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (10.5%)
Phase 27 (36.8%)
Phase 36 (31.6%)
Phase 42 (10.5%)
N/A2 (10.5%)

Trials by Status

active_not_recruiting210%
unknown15%
recruiting210%
completed1676%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT07154654

Prospective, Long Term, Observational Study (Patient Registry) of Paediatric Myotonic Disorders

Recruiting
NCT04622553Not Applicable

Open-label Extension Study in Paediatric Patients Who Have Completed the MEX-NM-301 Study.

Active Not Recruiting
NCT04616807

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Active Not Recruiting
NCT04624750Phase 3

Open Label Study in Adolescents and Children With Myotonic Disorders

Completed
NCT05619120Not Applicable

The Effect of Late Na Current Blocker Mexiletine on Giant T-wave Electrical Alternans(STOP-TWA)

Recruiting
NCT05017155Phase 3

MExiletine Versus Lamotrigine in Non-Dystrophic Myotonias

Unknown
NCT01849770Phase 2

Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)

Completed
NCT02781454Phase 2

Mexiletine in Sporadic Amyotrophic Lateral Sclerosis

Completed
NCT02260388Phase 4

Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations

Completed
NCT01406873Phase 2

Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1

Completed
NCT02561702Phase 2

Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease

Completed
NCT01811355Phase 4

Mexiletine for the Treatment of Muscle Cramps in ALS

Completed
NCT02308748Phase 1

Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block

Completed
NCT02045667Phase 2

Combined N-of-1 Trials Mexiletine vs Placebo in Patients With Non-Dystrophic Myotonia (NDM)

Completed
NCT00000518Phase 3

Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)

Completed
NCT02336477Phase 3

Mexiletine and Non Dystrophic Myotonias

Completed
NCT01717404Phase 1

Effects of Mexiletine on Colonic Transit in a Patient With Irritable Bowel Syndrome - Constipation (IBS-C)

Completed
NCT00832000Phase 2

Effectiveness of Mexiletine for Treating People With Non-Dystrophic Myotonia

Completed
NCT00000464Phase 3

Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)

Completed
NCT00001784Phase 2

Mexiletine for the Treatment of Focal Dystonia

Completed

Drug Details

Intervention Type
DRUG
Total Trials
21