Success Metrics

Clinical Success Rate
72.4%

Based on 21 completed trials

Completion Rate
72%(21/29)
Active Trials
6(16%)
Results Posted
76%(16 trials)
Terminated
8(22%)

Phase Distribution

Ph phase_1
2
5%
Ph phase_2
2
5%
Ph phase_3
10
27%
Ph phase_4
17
46%
Ph early_phase_1
1
3%
Ph not_applicable
3
8%

Phase Distribution

3

Early Stage

2

Mid Stage

27

Late Stage

Phase Distribution35 total trials
Early Phase 1First-in-human
1(2.9%)
Phase 1Safety & dosage
2(5.7%)
Phase 2Efficacy & side effects
2(5.7%)
Phase 3Large-scale testing
10(28.6%)
Phase 4Post-market surveillance
17(48.6%)
N/ANon-phased studies
3(8.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.4%

21 of 29 finished

Non-Completion Rate

27.6%

8 ended early

Currently Active

6

trials recruiting

Total Trials

37

all time

Status Distribution
Active(8)
Completed(21)
Terminated(8)

Detailed Status

Completed21
Terminated8
Recruiting4
Active, not recruiting2
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
37
Active
6
Success Rate
72.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.9%)
Phase 12 (5.7%)
Phase 22 (5.7%)
Phase 310 (28.6%)
Phase 417 (48.6%)
N/A3 (8.6%)

Trials by Status

active_not_recruiting25%
completed2157%
not_yet_recruiting25%
recruiting411%
terminated822%

Recent Activity

Clinical Trials (37)

Showing 20 of 37 trialsScroll for more
NCT07519161Not Applicable

Pharmacological Intervention to Prevent NOAF After TAVR

Not Yet Recruiting
NCT07490067Phase 4

Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score

Recruiting
NCT04434664Phase 4

BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF

Completed
NCT05931276Phase 3

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

Recruiting
NCT06964464Phase 4

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

Recruiting
NCT03778554Phase 4

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction

Active Not Recruiting
NCT05096884Early Phase 1

Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study

Terminated
NCT03278509Phase 4

Evaluation of Decreased Usage of Betablockers After Myocardial Infarction in the SWEDEHEART Registry (REDUCE-SWEDEHEART)

Active Not Recruiting
NCT01798992Phase 4

Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart

Completed
NCT05711810Phase 4

Medicine-induced Cardiac Hemodialysis on COVID-19

Completed
NCT01970501Phase 2

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure

Completed
NCT05066633Phase 3

The Efficacy and Safety of Metoprolol as add-on Treatment to Standard of Care in Preventing Cardiomyopathy in Patients With DMD

Recruiting
NCT02293096Not Applicable

Pharmacogenetic Prediction of Metoprolol Effectiveness

Terminated
NCT04996550

Are Carvedilol and Metoprolol Succinate Comparable Treatments in Heart Failure Patients With Reduced Ejection Fraction

Not Yet Recruiting
NCT03532802Phase 2

The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy.

Completed
NCT02587351Phase 3

Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Terminated
NCT01502787Phase 4

Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients

Completed
NCT00255502Phase 3

307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects

Completed
NCT03612180

Evaluation of Metoprolol Pharmacokinetics in Patients Receiving Hi Flux Hemodialysis

Completed
NCT01501929Phase 4

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Completed

Drug Details

Intervention Type
DRUG
Total Trials
37