Success Metrics

Clinical Success Rate
89.7%

Based on 78 completed trials

Completion Rate
90%(78/87)
Active Trials
33(24%)
Results Posted
51%(40 trials)
Terminated
9(6%)

Phase Distribution

Ph phase_2
52
37%
Ph phase_3
52
37%
Ph phase_1
10
7%
Ph phase_4
12
9%
Ph not_applicable
9
6%

Phase Distribution

10

Early Stage

52

Mid Stage

64

Late Stage

Phase Distribution135 total trials
Phase 1Safety & dosage
10(7.4%)
Phase 2Efficacy & side effects
52(38.5%)
Phase 3Large-scale testing
52(38.5%)
Phase 4Post-market surveillance
12(8.9%)
N/ANon-phased studies
9(6.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.6%

78 of 89 finished

Non-Completion Rate

12.4%

11 ended early

Currently Active

33

trials recruiting

Total Trials

139

all time

Status Distribution
Active(35)
Completed(78)
Terminated(11)
Other(15)

Detailed Status

Completed78
Recruiting19
unknown14
Active, not recruiting14
Terminated9
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
139
Active
33
Success Rate
89.7%
Most Advanced
Phase 4

Trials by Phase

Phase 110 (7.4%)
Phase 252 (38.5%)
Phase 352 (38.5%)
Phase 412 (8.9%)
N/A9 (6.7%)

Trials by Status

unknown1410%
not_yet_recruiting21%
completed7856%
active_not_recruiting1410%
withdrawn21%
terminated96%
recruiting1914%
suspended11%

Recent Activity

Clinical Trials (139)

Showing 20 of 139 trialsScroll for more
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT03959085Phase 3

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Recruiting
NCT02883049Phase 3

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Active Not Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03007147Phase 3

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT00558519Phase 2

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Completed
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT05848687Phase 1

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Recruiting
NCT04216524Phase 2

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

Recruiting
NCT02143414Phase 2

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02205762Phase 2

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Active Not Recruiting
NCT01503632Phase 3

Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission

Completed
NCT01190930Phase 3

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Active Not Recruiting
NCT06918431Phase 2

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
139