Success Metrics

Clinical Success Rate
89.9%

Based on 80 completed trials

Completion Rate
90%(80/89)
Active Trials
31(22%)
Results Posted
50%(40 trials)
Terminated
9(6%)

Phase Distribution

Ph phase_2
53
38%
Ph phase_4
12
9%
Ph not_applicable
9
6%
Ph phase_1
11
8%
Ph phase_3
52
37%

Phase Distribution

11

Early Stage

53

Mid Stage

64

Late Stage

Phase Distribution137 total trials
Phase 1Safety & dosage
11(8.0%)
Phase 2Efficacy & side effects
53(38.7%)
Phase 3Large-scale testing
52(38.0%)
Phase 4Post-market surveillance
12(8.8%)
N/ANon-phased studies
9(6.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.9%

80 of 91 finished

Non-Completion Rate

12.1%

11 ended early

Currently Active

31

trials recruiting

Total Trials

141

all time

Status Distribution
Active(35)
Completed(80)
Terminated(11)
Other(15)

Detailed Status

Completed80
Recruiting18
unknown14
Active, not recruiting13
Terminated9
Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials
141
Active
31
Success Rate
89.9%
Most Advanced
Phase 4

Trials by Phase

Phase 111 (8.0%)
Phase 253 (38.7%)
Phase 352 (38.0%)
Phase 412 (8.8%)
N/A9 (6.6%)

Trials by Status

unknown1410%
suspended11%
active_not_recruiting139%
recruiting1813%
terminated96%
withdrawn21%
completed8057%
not_yet_recruiting43%

Recent Activity

Clinical Trials (141)

Showing 20 of 141 trialsScroll for more
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT01503632Phase 3

Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission

Completed
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT03488225Phase 2

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

Terminated
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT00400946Phase 3

05-001: Treatment of Acute Lymphoblastic Leukemia in Children

Completed
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT07716735Phase 1

Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer

Not Yet Recruiting
NCT02143414Phase 2

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03020030Phase 3

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Active Not Recruiting
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT03959085Phase 3

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Recruiting
NCT00501826Phase 2

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recruiting
NCT01371630Phase 1

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Recruiting
NCT05303792Phase 2

Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT03571321Phase 1

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
141