Lonafarnib
Lonafarnib is a pharmaceutical drug with 25 clinical trials. Currently 2 active trials ongoing. Historical success rate of 84.2%.
Success Metrics
Based on 16 completed trials
Phase Distribution
Phase Distribution
6
Early Stage
15
Mid Stage
3
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
76.2%
16 of 21 finished
23.8%
5 ended early
2
trials recruiting
25
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Once Daily Dosing of Lonafarnib Co-administered With Ritonavir for Treatment of Chronic Hepatitis D Virus Infection
Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)
Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide
Titrating-Dose of Lonafarnib in Combination With Ritonavir
Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a
Clinical Trials (25)
Once Daily Dosing of Lonafarnib Co-administered With Ritonavir for Treatment of Chronic Hepatitis D Virus Infection
Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)
Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide
Titrating-Dose of Lonafarnib in Combination With Ritonavir
Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a
Lonafarnib Boosted With Ritonavir With and Without Peginterferon Alfa-2a (PEG IFN-a) in HDV (LOWR-2)
Lonafarnib With and Without Ritonavir in HDV (LOWR-1)
Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon
Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome or Progeroid Laminopathy
A Study of Lonafarnib With or Without Ritonavir in Patients With HDV
SCH 66336 With or Without Gemcitabine Followed by Surgery Compared With Surgery Alone in Treating Patients With Primary Liver Cancer
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria
A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria
Treatment of Chronic Delta Hepatitis With Lonafarnib and Ritonavir
Lonafarnib for Chronic Hepatitis D
Lonafarnib in Metastatic Breast Cancer
Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)
Anastrozole Plus Lonafarnib (SCH 66336) or Plus Placebo for the Treatment of Advanced Breast Cancer (P03480)
Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas
Combination Chemotherapy in Treating Patients With Advanced Cancer
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 25