Success Metrics

Clinical Success Rate
100.0%

Based on 5 completed trials

Completion Rate
100%(5/5)
Active Trials
1(17%)
Results Posted
80%(4 trials)

Phase Distribution

Ph phase_3
3
50%
Ph phase_2
1
17%
Ph phase_4
1
17%
Ph early_phase_1
1
17%

Phase Distribution

1

Early Stage

1

Mid Stage

4

Late Stage

Phase Distribution6 total trials
Early Phase 1First-in-human
1(16.7%)
Phase 2Efficacy & side effects
1(16.7%)
Phase 3Large-scale testing
3(50.0%)
Phase 4Post-market surveillance
1(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

5 of 5 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

6

all time

Status Distribution
Active(1)
Completed(5)

Detailed Status

Completed5
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
6
Active
1
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (16.7%)
Phase 21 (16.7%)
Phase 33 (50.0%)
Phase 41 (16.7%)

Trials by Status

completed583%
recruiting117%

Recent Activity

1 active trials
Showing 5 of 6
recruitingearly_phase_1

Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis

NCT07569419
completedphase_4

Effect to Linaclotide on Colonic Motility

NCT06989268
completedphase_2

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

NCT02270983
completedphase_3

Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating

NCT01642914
completedphase_3

Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation

NCT00948818
View all 6 trials

Clinical Trials (6)

Showing 6 of 6 trials
NCT07569419Early Phase 1

Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis

Recruiting
NCT06989268Phase 4

Effect to Linaclotide on Colonic Motility

Completed
NCT02270983Phase 2

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

Completed
NCT01642914Phase 3

Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating

Completed
NCT00948818Phase 3

Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation

Completed
NCT00765882Phase 3

Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation

Completed

All 6 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
6