Success Metrics

Clinical Success Rate
77.8%

Based on 7 completed trials

Completion Rate
78%(7/9)
Active Trials
15(58%)
Results Posted
143%(10 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_2
13
50%
Ph phase_3
10
38%
Ph phase_4
1
4%
Ph phase_1
2
8%

Phase Distribution

2

Early Stage

13

Mid Stage

11

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
2(7.7%)
Phase 2Efficacy & side effects
13(50.0%)
Phase 3Large-scale testing
10(38.5%)
Phase 4Post-market surveillance
1(3.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.0%

7 of 10 finished

Non-Completion Rate

30.0%

3 ended early

Currently Active

15

trials recruiting

Total Trials

26

all time

Status Distribution
Active(15)
Completed(7)
Terminated(3)
Other(1)

Detailed Status

Active, not recruiting12
Completed7
Recruiting3
Terminated2
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
15
Success Rate
77.8%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (7.7%)
Phase 213 (50.0%)
Phase 310 (38.5%)
Phase 41 (3.8%)

Trials by Status

active_not_recruiting1246%
withdrawn14%
recruiting312%
unknown14%
completed727%
terminated28%

Recent Activity

15 active trials
Showing 5 of 26

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT06065748Phase 3

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Recruiting
NCT05306340Phase 3

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Active Not Recruiting
NCT05296798Phase 3

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Active Not Recruiting
NCT04576455Phase 2

A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer)

Active Not Recruiting
NCT04961996Phase 3

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

Active Not Recruiting
NCT04546009Phase 3

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Active Not Recruiting
NCT03332797Phase 1

A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer

Active Not Recruiting
NCT05498272Phase 2

Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations

Recruiting
NCT03879577Phase 2

Assessing the Response Rate of Neo-adjuvant Taxotere and Trastuzumab in Nigerian Women With Breast Cancer

Active Not Recruiting
NCT06001762Phase 2

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

Active Not Recruiting
NCT00329043Phase 2

Sunitinib Malate With Hormonal Ablation for Patients Who Will Have Prostatectomy

Active Not Recruiting
NCT00567580Phase 3

Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer

Active Not Recruiting
NCT03944434Phase 2

FACILE: FeAsibility of First-line RiboCIclib in OLdEr Patients with Advanced Breast Cancer

Active Not Recruiting
NCT05891093Phase 3

Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)

Recruiting
NCT00430183Phase 3

Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer

Active Not Recruiting
NCT00288080Phase 3

Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer

Completed
NCT00005044Phase 3

Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Completed
NCT01823835Phase 1

A Study of GDC-0810 Single Agent or in Combination With Palbociclib and/or a Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer

Terminated
NCT03380806Phase 2

Prostate Boost Irradiation With Stereotactic Body RT (SBRT)

Unknown
NCT01790126Phase 2

The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
26