Success Metrics

Clinical Success Rate
72.1%

Based on 155 completed trials

Completion Rate
72%(155/215)
Active Trials
111(29%)
Results Posted
79%(122 trials)
Terminated
60(16%)

Phase Distribution

Ph early_phase_1
6
2%
Ph phase_2
186
48%
Ph phase_4
2
1%
Ph phase_1
125
32%
Ph not_applicable
6
2%
Ph phase_3
59
15%

Phase Distribution

131

Early Stage

186

Mid Stage

61

Late Stage

Phase Distribution384 total trials
Early Phase 1First-in-human
6(1.6%)
Phase 1Safety & dosage
125(32.6%)
Phase 2Efficacy & side effects
186(48.4%)
Phase 3Large-scale testing
59(15.4%)
Phase 4Post-market surveillance
2(0.5%)
N/ANon-phased studies
6(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.9%

155 of 239 finished

Non-Completion Rate

35.1%

84 ended early

Currently Active

111

trials recruiting

Total Trials

386

all time

Status Distribution
Active(119)
Completed(155)
Terminated(84)
Other(28)

Detailed Status

Completed155
Recruiting69
Terminated60
Active, not recruiting42
unknown28
Withdrawn24

Development Timeline

Analytics

Development Status

Total Trials
386
Active
111
Success Rate
72.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.6%)
Phase 1125 (32.6%)
Phase 2186 (48.4%)
Phase 359 (15.4%)
Phase 42 (0.5%)
N/A6 (1.6%)

Trials by Status

terminated6016%
unknown287%
withdrawn246%
completed15540%
not_yet_recruiting82%
recruiting6918%
active_not_recruiting4211%

Recent Activity

Clinical Trials (386)

Showing 20 of 386 trialsScroll for more
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT05203172Phase 4

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Recruiting
NCT03109288Phase 1

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Recruiting
NCT06780111Phase 1

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT06219941Phase 2

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT07733180Phase 2

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT07277270Phase 1

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

Recruiting
NCT05647122Phase 1

First in Human Study of AZD9592 in Solid Tumors

Active Not Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT06447662Phase 1

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Active Not Recruiting
NCT05863195Phase 3

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07409272Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
386