Success Metrics

Clinical Success Rate
72.4%

Based on 152 completed trials

Completion Rate
72%(152/210)
Active Trials
107(28%)
Results Posted
79%(120 trials)
Terminated
58(15%)

Phase Distribution

Ph not_applicable
6
2%
Ph phase_3
58
15%
Ph phase_4
1
0%
Ph early_phase_1
6
2%
Ph phase_1
124
33%
Ph phase_2
182
48%

Phase Distribution

130

Early Stage

182

Mid Stage

59

Late Stage

Phase Distribution377 total trials
Early Phase 1First-in-human
6(1.6%)
Phase 1Safety & dosage
124(32.9%)
Phase 2Efficacy & side effects
182(48.3%)
Phase 3Large-scale testing
58(15.4%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
6(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.0%

152 of 234 finished

Non-Completion Rate

35.0%

82 ended early

Currently Active

107

trials recruiting

Total Trials

379

all time

Status Distribution
Active(116)
Completed(152)
Terminated(82)
Other(29)

Detailed Status

Completed152
Recruiting64
Terminated58
Active, not recruiting43
unknown29
Withdrawn24

Development Timeline

Analytics

Development Status

Total Trials
379
Active
107
Success Rate
72.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.6%)
Phase 1124 (32.9%)
Phase 2182 (48.3%)
Phase 358 (15.4%)
Phase 41 (0.3%)
N/A6 (1.6%)

Trials by Status

withdrawn246%
completed15240%
not_yet_recruiting92%
recruiting6417%
unknown298%
active_not_recruiting4311%
terminated5815%

Recent Activity

Clinical Trials (379)

Showing 20 of 379 trialsScroll for more
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT05355701Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Recruiting
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT06219941Phase 2

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Recruiting
NCT07733180Phase 2

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Not Yet Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06835387Phase 2

Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

Recruiting
NCT03109288Phase 1

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Recruiting
NCT07409272Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Recruiting
NCT07415031Phase 2

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

Recruiting
NCT03203525Phase 1

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Terminated
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT07290985Phase 2

AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
379