Success Metrics

Clinical Success Rate
73.3%

Based on 148 completed trials

Completion Rate
73%(148/202)
Active Trials
110(29%)
Results Posted
78%(116 trials)
Terminated
54(14%)

Phase Distribution

Ph phase_1
121
32%
Ph phase_4
1
0%
Ph early_phase_1
6
2%
Ph not_applicable
6
2%
Ph phase_2
180
48%
Ph phase_3
58
16%

Phase Distribution

127

Early Stage

180

Mid Stage

59

Late Stage

Phase Distribution372 total trials
Early Phase 1First-in-human
6(1.6%)
Phase 1Safety & dosage
121(32.5%)
Phase 2Efficacy & side effects
180(48.4%)
Phase 3Large-scale testing
58(15.6%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
6(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.5%

148 of 226 finished

Non-Completion Rate

34.5%

78 ended early

Currently Active

110

trials recruiting

Total Trials

374

all time

Status Distribution
Active(118)
Completed(148)
Terminated(78)
Other(30)

Detailed Status

Completed148
Recruiting65
Terminated54
Active, not recruiting45
unknown30
Withdrawn24

Development Timeline

Analytics

Development Status

Total Trials
374
Active
110
Success Rate
73.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.6%)
Phase 1121 (32.5%)
Phase 2180 (48.4%)
Phase 358 (15.6%)
Phase 41 (0.3%)
N/A6 (1.6%)

Trials by Status

recruiting6517%
completed14840%
active_not_recruiting4512%
terminated5414%
withdrawn246%
unknown308%
not_yet_recruiting82%

Recent Activity

Clinical Trials (374)

Showing 20 of 374 trialsScroll for more
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT07076212Phase 2

Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma

Recruiting
NCT04248452Phase 3

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Active Not Recruiting
NCT05083481Phase 1

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Active Not Recruiting
NCT04233866Phase 2

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Active Not Recruiting
NCT05355701Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Recruiting
NCT05863195Phase 3

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Recruiting
NCT05146739Phase 1

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Active Not Recruiting
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT04481204Phase 2

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

Withdrawn
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT06469944Phase 1

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT00217737Phase 3

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT07554521Phase 2

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

Not Yet Recruiting
NCT06625320Phase 3

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Active Not Recruiting
NCT05239741Phase 3

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
374