LDE225
LDE225 is a pharmaceutical drug with 23 clinical trials. Historical success rate of 85.0%.
Success Metrics
Based on 17 completed trials
Phase Distribution
Phase Distribution
15
Early Stage
6
Mid Stage
0
Late Stage
Highest Phase Reached
Phase 2Trial Status & Enrollment
73.9%
17 of 23 finished
26.1%
6 ended early
0
trials recruiting
23
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer
Study of LDE225 (Sonidegib) in Combination With Docetaxel in Triple Negative (TN) Advanced Breast Cancer (ABC) Patients
Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients
Effect of Hepatic Impairment on LDE225..
An East Asian Study of LDE225
Clinical Trials (23)
Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer
Study of LDE225 (Sonidegib) in Combination With Docetaxel in Triple Negative (TN) Advanced Breast Cancer (ABC) Patients
Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients
Effect of Hepatic Impairment on LDE225..
An East Asian Study of LDE225
Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
LDE225 and Paclitaxel in Solid Tumors
A Phase II Study of Efficacy and Safety in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
LDE225 + Docetaxel/Prednisone for Adv/Met Castrate Resistant Prostate Cancer w/ Disease Progression After Docetaxel
A Pre-surgical Study of LDE225 in Men With High-risk Localized Prostate Cancer
LDE225 in Patients With Advanced or Metastatic Hepatocellular Carcinoma and Child-Pugh A/B7 Cirrhosis
Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT
A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
Safety/Efficacy Study of LDE225 (Sonidegib) Plus Bortezomib in Patients With Relapsed or Relapsed/Refractory Multiple Myeloma
Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors
Study of Efficacy and Safety of LDE225 in Adult Patients With Relapsed/Refractory Acute Leukemia
A Biomarker Study to Identify Predictive Signatures of Response to LDE225 (Hedgehog Inhibitor) In Patients With Resectable Pancreatic Cancer
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 23