Success Metrics

Clinical Success Rate
83.7%

Based on 72 completed trials

Completion Rate
84%(72/86)
Active Trials
3(3%)
Results Posted
61%(44 trials)
Terminated
14(15%)

Phase Distribution

Ph phase_2
55
57%
Ph phase_3
5
5%
Ph phase_1
34
35%

Phase Distribution

34

Early Stage

55

Mid Stage

5

Late Stage

Phase Distribution94 total trials
Phase 1Safety & dosage
34(36.2%)
Phase 2Efficacy & side effects
55(58.5%)
Phase 3Large-scale testing
5(5.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

79.1%

72 of 91 finished

Non-Completion Rate

20.9%

19 ended early

Currently Active

3

trials recruiting

Total Trials

96

all time

Status Distribution
Active(3)
Completed(72)
Terminated(19)
Other(2)

Detailed Status

Completed72
Terminated14
Withdrawn5
Active, not recruiting3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
96
Active
3
Success Rate
83.7%
Most Advanced
Phase 3

Trials by Phase

Phase 134 (36.2%)
Phase 255 (58.5%)
Phase 35 (5.3%)

Trials by Status

withdrawn55%
completed7275%
terminated1415%
active_not_recruiting33%
unknown22%

Recent Activity

Clinical Trials (96)

Showing 20 of 96 trialsScroll for more
NCT00977574Phase 2

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Active Not Recruiting
NCT01375829Phase 1

Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Active Not Recruiting
NCT00877500Phase 2

Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy

Active Not Recruiting
NCT01349088Phase 1

Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer

Withdrawn
NCT03393741

Pharmacodynamic Biomarkers of Standard Anti-microtubule Drugs as Assessed by Early Tumor Biopsy

Terminated
NCT03093155Phase 2

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Completed
NCT00630032Phase 3

Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer

Completed
NCT00765765Phase 1

Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer

Terminated
NCT00879086Phase 2

A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Participants With Advanced Breast Cancer

Completed
NCT02915744Phase 3

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine

Completed
NCT01446016Phase 2

Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT)

Completed
NCT00785291Phase 3

Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer

Completed
NCT00828308Phase 2

Neoadjuvant Weekly Ixabepilone for High Risk, Clinically Localized Prostate Cancer

Completed
NCT00741988Phase 2

Ixabepilone and Carboplatin +/- Bevacizumab in Advanced Non-Small-Cell Lung Cancer

Completed
NCT00866905Phase 2

Ixabepilone and Cyclophosphamide as Neoadjuvant Therapy in HER-2 Negative Breast Cancer

Completed
NCT01097642Phase 2

Neo-Adjuvant Study in Triple Negative Breast Cancer Patients

Completed
NCT00207090Phase 1

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

Completed
NCT00162136Phase 1

Clinical Study of Ixabepilone Administered as a 24 Hour Infusion in Patients With Solid Malignancies.

Completed
NCT00983801Phase 2

Study of Ixabepilone in Asian Subjects With Unresectable or Metastatic Gastric Cancer

Completed
NCT00832117Phase 1

Phase I Combination Ixabepilone + Cisplatin

Completed

Drug Details

Intervention Type
DRUG
Total Trials
96