Success Metrics

Clinical Success Rate
76.7%

Based on 264 completed trials

Completion Rate
77%(264/344)
Active Trials
135(22%)
Results Posted
55%(144 trials)
Terminated
80(13%)

Phase Distribution

Ph phase_4
4
1%
Ph early_phase_1
7
1%
Ph not_applicable
7
1%
Ph phase_2
312
51%
Ph phase_1
188
31%
Ph phase_3
87
14%

Phase Distribution

195

Early Stage

312

Mid Stage

91

Late Stage

Phase Distribution605 total trials
Early Phase 1First-in-human
7(1.2%)
Phase 1Safety & dosage
188(31.1%)
Phase 2Efficacy & side effects
312(51.6%)
Phase 3Large-scale testing
87(14.4%)
Phase 4Post-market surveillance
4(0.7%)
N/ANon-phased studies
7(1.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.1%

264 of 361 finished

Non-Completion Rate

26.9%

97 ended early

Currently Active

135

trials recruiting

Total Trials

608

all time

Status Distribution
Active(152)
Completed(264)
Terminated(97)
Other(95)

Detailed Status

Completed264
unknown93
Recruiting85
Terminated80
Active, not recruiting50
Withdrawn17

Development Timeline

Analytics

Development Status

Total Trials
608
Active
135
Success Rate
76.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.2%)
Phase 1188 (31.1%)
Phase 2312 (51.6%)
Phase 387 (14.4%)
Phase 44 (0.7%)
N/A7 (1.2%)

Trials by Status

recruiting8514%
withdrawn173%
active_not_recruiting508%
terminated8013%
not_yet_recruiting163%
suspended20%
enrolling_by_invitation10%
unknown9315%
completed26443%

Recent Activity

Clinical Trials (608)

Showing 20 of 608 trialsScroll for more
NCT05319730Phase 1

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT05235542Phase 1

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Completed
NCT04607421Phase 3

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT07328425Phase 2

Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS

Recruiting
NCT05083481Phase 1

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Terminated
NCT06450041Phase 2

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

Recruiting
NCT04587128Phase 2

Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC

Active Not Recruiting
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT04879368Phase 3

RegoNivo vs Standard of Care Chemotherapy in AGOC

Completed
NCT07214298Phase 1

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT06750094Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Recruiting
NCT07085338Phase 2

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Recruiting
NCT05669339Phase 2

AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

Recruiting
NCT07619313Phase 1

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

Not Yet Recruiting
NCT04753879Phase 2

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Active Not Recruiting
NCT06625320Phase 3

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Active Not Recruiting
NCT07409272Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
608